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School of Pharmacy
Basic Pharmaceutical Sciences

Publications of Dr. Khalid ElSayed

Book Chapters

5. Foudah AI, Sallam A, El Sayed KA. 2014. Discovery and computer-aided drug design studies of the anticancer marine triterpene sipholanes as novel P-gp and Brk modulators. Anticancer Drugs from Marine Origin, Springer, 2015, pp 547-569. Se-Kwon Kim, Editor. DOI 10.1007/978-3-319-07145-9_26.  ISBN: 978-3-319-07144-2
4. Mudit M, Khanfar M, Shah GV, El Sayed KA. 2011. Discovery, design, and development of anti-invasive natural product leads. Methods in Molecular Biology Protocols- Drug Design and Discovery, Humana Press (ISSN: 1064-3745) Volume 716, Chapter 4, 55-76.
3. Arif JM, Kunhi M, Siddiqui YM, El Sayed KA, Orabi KY, Al-Hazzani A, Al-Ahdal MN, Al-Khodairy FM. 2010. Differential modulation of benzo[a]pyrene-derived DNA adducts in MCF-7 cells by marine compounds. DNA Adducts, Conference Proceeding, Edited by Alvarez, Emerson; Cunha, Roberto, pages 127-142, ISBN: 978-1-60741-433-9.
2. El Sayed KA. Studies in Natural Product Chemistry: Natural products as antiviral agents, Elsevier
Science Publishers, Amsterdam, Atta-ur-Rahman, Editor. 2000; 24:473-572.
1. El Sayed KA, Dunbar DC, Bartyzel P, Day W, Zjawiony J, Hamann MT. Biologically active products:
Pharmaceuticals: Marine natural product as antiinfective agents, CRC Press, Cutler, S.J. & Cutler, H., Editors, 2000; 233-252, ISBN: 0-8493-1887-4.

Original Articles

139. Ayoub NM, Siddique AB, Ebrahim HY, Mohyeldin MM, El Sayed KA. The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment. Eur J Pharmacol, 2017, 810, 100–111
138. Acylated iridoids and rhamnopyranoses from Premna odorata (Lamiaceae) as novel mesenchymal-epithelial transition factor receptor inhibitors for the control of breast cancer. Elmaidomy AH, Mohyeldin MM, Ibrahim MM, Hassan HM, Amin E, Rateb ME, Hetta MH, El Sayed KA. Phytotherapy Research, 2017, In Press: DOI: 10.1002/ptr.5882
137. Mady MS, Houssen W, Abdou R, Haggag EG, El Sayed KA. Bioactive secondary metabolites isolated from endophytic fungus Penicillium citrinium associated with olive tree fruit. Journal of Advanced Pharmacy Research, 2017, 1, 160-170. DOI: 10.21608/APRH.2017.3361
136. Elsayed HE, Ebrahim HE, Mohyeldin MM, Siddique A, Haggag EG, Kamal AM, El Sayed KA. Rutin as a novel c-Met inhibitory lead for the control of breast malignancies. Nutrition & Cancer, N&C-04-16-2695.R3, Accepted July 24, 2017
135. Batarseh YS, Mohamed LA, Al Rihani SB, Mousa YM, Siddique A, El Sayed KA, Kaddoumi A. Oleocanthal ameliorates amyloid-β oligomers toxicity on astrocytes and neuronal cells: In-vitro studies. Neuroscience 2017, 352, 204–215. PMID: 28392295
134. Hailat M, Ebrahim HY, Siddique A, Goda A, El Sayed KA. (1S,2E,4S,7E,11E)-2,7,11-cembratriene-4,6-diol as a novel angiogenesis inhibitor for the control of triple negative breast malignancies. Bioorganic Med. Chem. 2017, 25, 3911-3921
133. Elsayed HE, Ebrahim HY, Haggag EG, Kamal AM, El Sayed KA. Rationally designed hecogenin thiosemicarbazone analogs as novel MEK inhibitors for the control of breast malignancies. Bioorg Med Chem. BMC_2017_1106, Submitted July 20, 2017
132. Ebrahim HY, Akl M, Elsayed H, Hill, R, El Sayed KA. Usnic acid benzylidene analogs as potent mTOR inhibitors for the control of breast malignancies. J Nat Prod, 2017, 80, 932−952. PMID: 28245124
131. Palem JR, Mudit M, Hsia SCV, El Sayed KA. Discovery and preliminary structure-activity relationship of the marine natural products manzamines as herpes simplex virus type-1 inhibitors. Zeitschrift für Naturforschung C, 2017, 72(1-2), 49-54. PMID: 27447204
130. Mohyeldin MM, Akl MR, El Sayed KA. The marine-derived pachycladin diterpenoids as novel wild and mutant EGFR inhibitors. Biochem Pharmacology, 2017, 126, 51-68. PMID: 27940262 
129. Ebrahim HY, Moheyldin MM, Hailat MM, El Sayed KA. (1S,2E,4S,7E,11E)-2,7,11-Cembratriene-4,6-diol semisynthetic analogs as novel c-Met inhibitors for the control of c-Met-Dependent breast malignancies. Bioorg Med Chem, 2016, 24, 5748-5761. PMID: 27681240
128. Goda A, Naguib K, Mohamed M, Amra H, Nada S, Abdel-Ghaffar AR, Gissendanner CR, El Sayed KA Astaxanthin and docosahexaenoic acid reverse the toxicity of the Maxi-K (BK) channel antagonist mycotoxin penitrem A. Marine Drugs. 2016, 14, 208; doi:10.3390/md14110208
127. Mudit M, El Sayed KA. Cancer control potential of marine natural product scaffolds through inhibition of tumor cellular migration and invasion. Drug Discovery Today, 2016, 21, 1745-1760
126. Ebrahim HY, Elsayed HE, Mohyeldin MM, Akl MR,  Bhattacharjee J, Egbert S, El Sayed KA. Norstictic acid inhibits breast cancer cell proliferation, migration, invasion, and in vivo invasive growth through targeting c-Met. 2016. Phytotherapy Research, 30, 557566  
125. Mohyeldin MM, Akl MR, Dragoi AM, Cardelli JA, El Sayed KA. The oleocanthal-based homovanillyl sinapate as a novel c-Met inhibitor. 2016. Oncotarget, 7, 32247-32273  
124. Mohyeldin MM, Busnena BA, Akl MR, Dragoi AM, Cardelli JA, El Sayed KA. Novel c-Met inhibitory olive secoiridoid semisynthetic analogs for the control of invasive breast cancer. 2016. Eur J Med Chem. 118, 299-315  
123. Ebrahim HY, El Sayed KA. Antiangiogenic marine natural product scaffolds. 2016. Marine Drugs, 14, 57; doi:10.3390/md14030057  
122. Mady MS, Mohyeldin MM, Ebrahim HY, Elsayed HE, Houssen WE, Haggag EG, Soliman RF, El Sayed KA. The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer proliferation, migration and invasion. 2016. Bioorg Med Chem. 24, 113-122  
121. Qosa H, Batarseh Y, Mohyeldin M, El Sayed KA, Keller J, Kaddoumi A.Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier model. ACS Chemical Neuroscience. 2015. 6(11), 1849-1859  
120. Abu-Fayyad A, Behery F, Sallam A, Alqahtani S, Ebrahim H, El Sayed KA, Kaddoumi A, Sylvester PW, Carroll JL, Cardelli JA, Nazzal S. PEGylated γ-tocotrienol isomer of vitamin E: Synthesis, characterization, in vitro cytotoxicity, and oral bioavailability. 2015, Eur J Pharm Biopharm, 96, 185-195  
119. Gray AL, Coleman DT, Castorea RF, Mohyeldin MM, El Sayed KA, Cardelli JA. Isothiocyanatostilbenes as novel c-Met inhibitors. 2015. Oncotarget, 6(38), 41180-41193  
118. Khanfar MA, Bardaweel SK, Akl MR, EI Sayed KA. Olive oil-derived oleocanthal as potent inhibitor of mammalian target of rapamycin: Biological evaluation and molecular modeling studies. 2015. Phytotherapy Research, 29(11), 1776-1782
117. Zhang Y, Zhang Y-K, Wang Y-J, Vispute SG, Jain S,  Li J, Chen Y, Youssef DTA, El Sayed KA, Chen ZS. Esters of the marine-derived triterpene sipholenol A reverse P-gp-mediated drug resistance. 2015. Marine Drugs, 13, 2267-2286 
116. Martins AH, Hu J,  Xu Z, Mu C, Alvarez P, Ford BD, El Sayed K, Eterovic VA, Ferchmin PA, Hao J. Neuroprotective activity of (1S,2E,4R,6R,-7E,11E)-2,7,11-cembratriene-4,6-diol (4R) in vitro and in vivo in rodent models of brain ischemia. 2015. Neuroscience, 291, 250-259 
115. Akl MR, Ayoub NM, Ebrahim HY, Foudah AI, Mohyeldin MM, Orabi KY, El Sayed KA. Araguspongine C induces autophagic death in breast cancer cells through suppression of c-Met and HER2 receptor tyrosine kinase signaling. 2015. Marine Drugs, 13, 288-311 
114. Ananthula S, Parajuli P, Behery FA, Alayoubi AY, Nazza Sl, El Sayed KA, Sylvester PW. 2014. Oxazine derivatives of 𝛾-and 𝛿-tocotrienol display enhanced anticancer activity in vivo,” Anticancer Research, 34, 2715-2726 
113. Ananthula S, Parajuli P, Behery FA, Alayoubi AY, Nazza Sl, El Sayed KA, Sylvester PW. 2014. 𝛿-Tocotrienol oxazine derivative antagonizes mammary tumor cell compensatory response to CoCl2-induced hypoxia. BioMed Research International Volume 2014, Article ID 285752, http://dx.doi.org/10.1155/2014/285752 
112. Sallam AA, Mohyeldin MM, Foudah AI, Akl MR, Nazzal SM, Meyer SA, Yong-Yu Liu YY, El Sayed KA. Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling. 2014. Organic & Biomolecular Chemistry 12, 5295–5303 
111. Akl MR, Elsayed HE, Ebrahim HY, Haggag EG, Kamal AM, El Sayed KA. 3-O-[N-(p-fluorobenzenesulfonyl)-carbamoyl]-oleanolic acid, a semisynthetic analog of oleanolic acid, induces apoptosis in breast cancer cells. 2014. European Journal of Pharmacology. 740, 209–217 
110. Elsayed HE, Akl MR, Ebrahim HY, Sallam AA,  Haggag EG, Kamal AM, El Sayed KA. Discovery, optimization and pharmacophore modeling of oleanolic acid and analogs as breast cancer cell migration and invasion inhibitors via targeting Brk/Paxillin/Rac1 axis. 2015. Chemical Biology & Drug Design 85, 231-243 
109. Akl MR, Busnena1 BA, Mohyeldin MM, Foudah AI, Ayoub NM, Liu YY, El Sayed KA. Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models. 2014. PlosOne. May 2014, 9 ( 5) e97622 
108. Akl M, Foudah A, Ebrahim H, El Sayed KA. The marine-derived sipholenol A-4-O-3′,4′-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through suppression of Brk and FAK signaling. 2014. Marine Drugs 12, 2282-2304 
107. Foudah A, Sallam A, Akl M, El Sayed KA. Optimization, pharmacophore modeling, and 3D-QSAR studies of sipholanes as breast cancer migration and proliferation inhibitors. 2014. European Journal of Medicinal Chemistry. 73 (2) 310-324
106. Sallam AA, Ayoub NA, Foudah AI, Gissendanner CR, Meyer SA, El Sayed KA. Indole diterpene alkaloids as novel inhibitors of the Wnt/b-catenin pathway in breast cancer cells. 2013. European Journal of Medicinal Chemistry. 70, 594-606
105. Sallam AA, Houssen WE., Foudah AI, Gissendanner CR, Orabi KY, El Sayed KA. 2013. Discovery and pharmacophore modeling of the mycotoxic indole diterpene alkaloids penitrems as breast cancer proliferation, migration, and invasion inhibitors. Medicinal Chemistry Communication 4 (10), 1360-1369
104. El Sayed KA, Foudah AI, Mayer AMS, Crider AM, Song D. Synthesis, microbial transformation, and pharmacological evaluation of 4,5-dihydronaphtho[2,1-b]furan-2-ones and related analogues. 2013. Medicinal Chemistry Communication, 4, 1231-1238
103. El Sayed KA, Chelette, CT. 2014. Design and evaluation of laboratory exercises to teach clinically-relevant chemistry of antibiotics using chemical and spectral experimental approaches. American Journal of Pharmaceutical Education, 78(2), Article 37
102. Orabi KY, Abaza MS, El Sayed KA, Elnagar AY, Al-Attiyah RJ, Guler RP. Selective growth inhibition of human malignant melanoma cells by syringic acid-derived proteasome inhibitors. 2013. Cancer Cell International 13, 82 (http://www.cancerci.com/content/13/1/82).
101. Abuznait A, Qosa H, Busnena B, El Sayed KA, Kaddoumi A. Olive oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer’s disease: In-vitro and in-vivo studies. 2013. ACS Chemical Neuroscience. 4(6), 973-982
100. Ibrahim SRM, Mohamed GA, Shaala LA, El Sayed KA, Youssef DTA. New alkaloids from Pancratium maritimum L. 2013. Planta Medica 79, 1480-1484
99. Foudah IA, Jain S, Busnena B, El Sayed K. Optimization of the marine triterpene sipholenols as inhibitors of breast cancer migration and invasion. ChemMedChem, 2013, 8, 497-510.
98. Busnena B, Foudah AI, Melancon T, El Sayed K. Olive secoiridoids and semisynthetic bioisosteres for the control of metastatic breast cancer. Bioorganic Medicinal Chemistry, 2013 21, 2117-21127
97. Metwally K, Khalil A, Sallam A, Pratsinis H, Kletsas D, El Sayed KA. 2013. Anticancer 3-methyl-2,5-diarylpyrimido[4,5-c]quinolin-1(2H)-ones: Structure-activity relationship of methoxy substitution. Medicinal Chemistry Research 22, 4481-4491
96. Eterović VA, Del Valle-Rodriguez1 A, Pérez D, El Sayed KA, Ferchmin PA. 2013. Protective activity of (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol analogues against diisopropylfluorophosphate neurotoxicity. Bioorganic Medicinal Chemistry 21, 4678-4686
95. Khanfar M.A., El Sayed K.A. The Veratrum alkaloids jervine, veratramine, and their analogues as prostate cancer migration and proliferation inhibitors. 2013. Medicinal Chemistry Research 22, 4775-4786
94. Fathy A. Behery, Mohamed R. Akl, Suryatheja Ananthula, Parash Parajuli, Paul W. Sylvester, Khalid A. El Sayed. 2013, Discovery and optimization of tocotrienol electrophilic substitution products as antiproliferative and antimigratory leads. European Journal of Medicinal Chemistry 48, 329-341
93. Behery F, Sallam A, El Sayed KA. 2012. Mannich- and Lederer-Manasse-based analogues of the natural product S (+)-curcuphenol as cancer proliferation and migration inhibitors.Med. Chem. Comm. 3, 1309-1315
92. Abraham I, El Sayed KA, Chen ZS, Guo H. Current status on marine natural products with reversal effect on cancer multidrug resistance. 2012. Marine Drugs, 10, 2312-2321
91. Shaala LA, Youssef DTA, Sulaiman M, Behery FA, Foudah AI, El Sayed KA. Subereamolline A as a potent breast cancer migration, invasion and proliferation inhibitor and bioactive dibrominated alkaloids from the Red Sea sponge Pseudoceratina arabica. 2012. Marine Drugs, 10, 2492-2508
90. Abuznait AH, Qosa H, O’Connell ND, Akbarian-Tefaghi J, Sylvester PW, El Sayed KA, Kaddoumi A. 2011. Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products. Food & Chemical Toxicology. 49 (11) 2765-2772
89. Hassan HM, Sallam AA, Mohammed R, Hifnawy MS, Youssef DTA, El Sayed KA. 2011. Semisynthetic analogues of the marine cembranoid sarcophine as prostate and breast cancer migration inhibitors. Bioorg. Med. Chem. 19, 4928-4934
88. Ramasahayam S, Baraka H, Abdelbar F, Abu Asal B, Widrlechner MP, ELSayed KA, Meyer SA. 2011. Effects of chemically characterized fractions from aerial parts of Echinacea purpurea and E. angustifolia on myelopoiesis in rats. Planta Medica 77 (17), 1883-1889
87. Hassan HM, Khanfar MA, Elnagar AY, Mohammed R, Shaala LA, Youssef DTA, Hifnawy MS, El Sayed KA. 2011. Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors. European Journal of Medicinal Chemistry 46 (4) 1122-1130
86. Aqil F, Zahin M, El Sayed KA, Ahmad I, Orabi KY, Arif JM. 2011. Antimicrobial, antioxidant, and antimutagenic activities of selected marine natural products and tobacco cembranoids. Drug and Chemical Toxicology 34(2): 167–179
85. Mudit M, El Sayed KA. 2011. Optimization of phenylmethylene hydantoins as prostate cancer migration inhibitors: SAR-directed design, synthesis, and pharmacophore modeling. Chemistry & Biodiversity, 8(8), 1470-1485
84. Baraka HN, Khanfar MA, Williams JC, El-Giar EM, El Sayed KA. 2011. Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids. Planta Medica 77(5), 467-476
83. Khanfar MK, El Sayed KA. 2011. Phenylmethylene hydantoins as prostate cancer invasion and migration inhibitors. CoMFA Approach and QSAR analysis. European J Med. Chem 45, 5397-5405. PMID: 2086913
82. Elnagar AY, Sylvester PW, El Sayed KA. 2011. (-)-Oleocanthal as a c-Met inhibitor for the control of metastatic breast and prostate cancers. Planta Medica. 77, 1013-1019
81. Abraham I, Jain S, Wu CP, Kuanga Y, Shia Z, Chen X, Khanfar M, Fu L, Ambudkar SV, El Sayed KA, Chen ZS. 2010. Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells. Biochemical Pharmacology 80, 1497-1506
80. Khanfar MK,Hill RA, Kaddoumi A,El Sayed KA. 2010. Combined ligand and structure-based virtual screening for identification of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability. J Med. Chem. 53(24), 8534-8545
79. Ali H, El Sayed KA, Sylvester PW, Nazzal S. 2010. Molecular interaction and localization of tocotrienol-rich fraction (TRF) within the matrices of lipid nanoparticles: Evidence studies by differential scanning calorimetry (DSC) and proton nuclear magnetic resonance spectroscopy (1H NMR). Colloids and Surfaces B: Biointerfaces, 77, 286-277
78. Sylvester PW, Kaddoumi A, Nazzal S, El Sayed KA. 2010. The Value of tocotrienols in the prevention and treatment of cancer. J Am. College Nutr. 29, 324S-333S
77. Behery FA, Elnagar AY, Wali VB, Abu Asal B, Kadduomi A, Sylvester PW, El Sayed KA. 2010. Redox-silent tocotrienol esters as breast cancer proliferation and migration inhibitors. Bioorganic & Medicinal Chemistry, 18, 8066-8075
76. Hassan HM, Khanfar MA, Elnagar AY, Mohammed R, Shaala LA, Youssef DTA, Hifnawy MS, El Sayed KA. 2010. Pachycladins A-F: Prostate cancer invasion and migration inhibitory eunicellin-based diterpenoids from the Red Sea soft coral Cladiella pachyclados. Journal of Natural Products. 73, 848–853
75. Mudit M, Behery FB, Wali VB, Sylvester PW, El Sayed KA. 2010. Toward molecular target identification of anticancer natural products: Fluorescent coumarin tagging of 4-hydroxyphenyl-methylene hydantoin and d-tocotrienol. Nat. Prod. Comm. 5, 1623-1626
74. Palem JR, Bedadala GR, El Sayed KA, Hsia SV. 2010. The marine-derived manzamine alkaloids as novel HSV-1 inhibitors. Planta Medica 76, 1-6
73. Sallam AA, Ramasahayam S, Meyer SA, El Sayed KA. 2010. Design, synthesis, and biological evaluation of dibromotyrosine analogues inspired by marine natural products as inhibitors of human prostate cancer proliferation, invasion, and migration. Bioorganic & Medicinal Chemistry 18, 7446–7457
72. Khanfar MA, El Sayed KA. 2010. 3D-QSAR Studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches. European Journal of Medicinal Chemistry 45, 3662-3668
71. Abdel Bar FM, Khanfar MA, Elnagar AY, Badria FA, Zaghloul AM, Ahmad KA, Sylvester PW, El Sayed KA. 2010. Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors. Bioorganic & Medicinal Chemistry 18, 496–507
70. Elnagar AY, Wali V, Sylvester PW, El Sayed KA. 2010. Design and preliminary structure-activity relationship of redox-silent semisynthetic tocotrienol analogues as inhibitors for breast cancer proliferation and invasion. Bioorganic & Medicinal Chemistry 18, 755–768
69. Khanfar M, Youssef DTA, El Sayed KA. 2010. Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: Biological evaluations, preliminary structure-activity relationship and molecular modeling studies. ChemMedChem 5, 274-285
68. Abdel Bar FM, Khanfar MA, Elnagar AY, Liu H, Zaghloul AM, Badria FA, Sylvester PW, Ahmad KA, Raisch KP, El Sayed KA. 2009. Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors. Journal of Natural Products 72, 1643-1650
67. Khanfar, M, Abu Asal B, Mudit M, Kadduomi A, El Sayed KA. 2009. The marine natural-derived inhibitors of glycogen synthase kinase-3β phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modeling. Bioorganic & Medicinal Chemistry 17, 6032-6039
66. Jain, S, Abraham I, Carvalho P, Kuang Y-H, Youssef DTA, Avery MA, Chen ZS, El Sayed KA. 2009. The marine sipholane terpenoids: Novel structures, reversal of ABCB1/P-glycoprotein-mediated multidrug resistance, and pharmacophore modeling. Journal of Natural Products 72, 1291-1298
65. Mudit Mudit, Mohammad Khanfar, Anbalagan Muralidharan, Shibu Thomas, Girish V. Shah, and Khalid El Sayed. 2009. Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products. Bioorganic & Medicinal Chemistry 17, 1531-1538
64. Girish V. Shah, Anbalagan Muralidharan, Shibu Thomas, Mitan Gokulgandhi, Mudit Mudit, Mohammad Khanfar, Khalid El Sayed. 2009. Identification of a small molecule(s) class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis. Molecular Cancer Therapeutics 8, 509-520
63. Yu B-Z, Kaimal R, BaiS, El SayedKA, Tatulian S, Apitz R, Jain M, uitang Deng R, Berg OG. 2009. Effect of cembranoids of Commiphora mukul on pancreatic phospholipase A2: Role in hypocholesteremia. Journal of Natural Products 72, 24-28
62. Radwan MR, Manly SP, El Sayed KA, Wali VB, Sylvester PW, Awate B, Shah G, Ross SA. 2008. Sinulodurin A and B, anticancer diterpenes from the soft coral Sinularia dura. Journal of Natural Products 71, 1468-1471
61. Abdel Bar FM, Zaghloul AM, Bachawal SV, Sylvester PW, Ahmad KF,El Sayed KA. 2008. Antiproliferative triterpenes from Melaleuca ericifolia. Journal of Natural Products 71, 1787-1790.
60. El Sayed KA, Shallal HM, Khanfar M, Muralidharan A, Thomas S, Youssef DTA, Zhou YD, Nagle DG, Shah G. 2008. Latrunculin A and Its C-17-O-Carbamates Inhibit Prostate Cancer Invasion and Breast Cancer HIF-1 Activation. Journal of Natural Products. 71, 396-402.
59. El Sayed KA, Laphookhieo S, Baraka HN, Yousaf M, Hebert A, Bagaley D, Rainey FA, Muralidharan A, Thomas S, Shah G. 2008. Biocatalytic and semisynthetic optimization of the anti-invasive tobacco (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol.Bioorganic Medicinal Chemistry. 16, 2886-2893.
58. El Sayed KA, Laphookhieo S, Prestridge J, Wali VB, Shirode AB, Sylvester PW. 2008. Semisynthetic and transformation studies of (1S,2E,4S,6R,7E,11E)-2,7,11-cembratriene-4,6-diol. Journal of Natural Products 71, 117-122.
57. El Sayed KA, Khalil AA, Yousaf, M., Labadie G., Mahesh K. Gundluru M.K., Franzblau S.G., Mayer AMS., Avery M., Hamann M.T. 2008. Semisynthetic studies on the manzamine alkaloids. Journal of Natural Products. 71, 300-308
56. Jain S, Laphookhieo S, Shi Z, Fu L, Akiyama S, Chen ZS, Youssef DTA, van Soest RWM, El Sayed KA. 2007. Reversal of P-glycoprotein-mediated multidrug resistance by sipholane triterpenoids. Journal of Natural Products. 70, 928-931
55. Ibrahim SRM, Badr JM, El Sayed KA, Youssef DTA. 2007. A new cytotoxic sesquiterpene and three anti-inflammatory flavonoids of the Egyptian Tanacetum santolinoides. Natural Product Communications 2, 1071-1074.
54. Sylvester PW, Wali VB, Shirode AB, Bachawal SV, El Sayed KA. 2007. Tocotrienols are the most potent anticancer agents in the vitamin E family of compounds. Curr. Research in Cancer, 1, 55-75.
53. Shi Z, Jain S, Kim IW, Peng XX, Abraham, I, Fu L, Youssef DT, El Sayed KA, Ambudkar SV, Gottesman MM, Chen ZS. 2007. Sipholenol A, a marine-derived sipholane triterpene, potently reverses P-glycoprotein-mediated (ABCB1)-mediated multidrug resistance in cancer cells. Cancer Science. 98, 1373-1380.
52. Jain S, Shirode A, Yacoub S, Barbo A, Sylvester PW, Huntimer E, Halaweish F, El Sayed KA. 2007. Biocatalysis of the anticancer sipholane triterpenoids. Planta Medica. 70, 591-596.
51. El Sayed KA, Sylvester PW. 2007. Biocatalytic and semisynthetic studies of the anticancer tobacco cembranoids. Expert Opinion on Investigational Drugs. 16, 877-887.
50. Orabi KY, El Sayed KA. 2007. Biocatalytic studies of the furanocoumarins angelicin and chalepensin. Natural Product Communications, 2, 565-569.
49. Arif JM, Sawant SS, El Sayed KA, Kunhi M, Subramanian MP, Siddiqui YM, Youssef DTA, Al-Hussain K, Mohammed N, Al-Ahdal MN, Al-Khodairy F. 2007. Antiproliferative potential of sarcophine and its semisynthetic sulfur-containing derivatives against human mammary carcinoma cell lines. Journal of Natural Medicines, 61, 154-158.
48. Sawant SS, Youssef DTA, Sylvester PW, Wali V, El Sayed KA. 2007.  Antiproliferative sesquiterpenes from the Red Sea soft coral Sarcophyton glaucum. Natural Product Communications, 2, 117-119.
47. Sawant SS, Youssef DTA, Reiland J, Ferniz M, Marchetti D, El Sayed KA. 2006 Biocatalytic and antimetastatic studies on the Red Sea soft coral Sarcophyton glaucum terpenes. Journal of Natural Products, 69, 1010-1013.
46. Sawant SS, Youssef DTA, Mayer AMS, Sylvester PW, Wali V, Arant ME, El Sayed KA. 2006. Anticancer and anti-inflammatory sulfur-containing semisynthetic derivatives of sarcophine. Chemical and Pharmaceutical Bulletin, 69, 1010-1013.
45. El Sayed KA, Youssef DTA, Marchetti D. 2006, Bioactive natural and semisynthetic latrunculins. Journal of Natural Products. 69, 219-223.
44. Sawant SS, Sylvester PW, Avery MA, Desai P, Youssef DTA, El Sayed KA. Bioactive rearranged and halogenated semisynthetic derivatives of the marine natural product sarcophine. Journal of Natural Products. 2004; 67:2017-2023.
43. Arif JM, Kunhi M, Siddiqui YM, El Sayed KA, Orabi KY, Al-Hazzani A, Al-Ahdal MN, Al-Khodairy FM. Role of intermediary biomarkers in determining the anticancer efficacy of marine compounds.Medicinal Chemistry Research, 2004; 13:553-562.
42. Arif JM, Kunhi M, Siddiqui YM, El Sayed KA, Orabi KY, Al-Hazzani A, Al-Ahdal MN, Al-Khodairy FM. Differential modulation of benzo[a]pyrene-derived DNA adducts in MCF-7 cells by marine compounds.International Journal of Cancer Prevention, 2004, 1, 89-97.
41. El Sayed KA. Natural products as angiogenesis modulators. Mini Reviews in Medicinal Chemistry, 2005, 5, 971-993.
40. Ahmed B, Al-Rehaily AJ, Al-Howiriny TA, El Sayed KA, Ahmed MS. Scropolioside-D2 and Harpagoside-B: Two new iridoid glycosides from Scrophularia deserti and their antidiabetic and antiinflammatory activity. Biological Pharmaceutical Bulletin, 2003, 26:462-467.
39. Khalil AA, El Sayed KA, Belal F, Khalil NY, Hamann MT. Spectrofluorimetric determination of manzamine A in spiked human urine and plasma. Pharmazie, 2003, 58:385-388.
38. Gochfeld DJ, El Sayed KA, Yousaf M, Hu J, Bartyzel P, Dunbar DC, Wilkins SP, Zjawiony JK, Schinazi RF, Schlueter Witrz S, Tharnish PM, Hamann MT. Marine natural products as lead anti-HIV agents.Mini Reviews in Medicinal Chemistry, 2003, 3:451-475.
37. Khalil AT, Maatooq GT, El Sayed KA. Limonoids from Citrus reticulata. Zeitschrift fuer Naturforschung, C: Journal of Biosciences, 2003; 58:165-170.
36. Peng J, Shen X, El Sayed KA, Dunbar DC, Perry TL, Wilkins SP, Hamann MT, Bobzin S, Huesing J, Camp R, Prinsen Mike, Krupa Dan, Wideman MA. Marine natural products as prototype agrochemicalagents. Journal of Agricultural and Food Chemistry, 2003; 51:2246-2252.
35. El Sayed KA, Yousaf M, Hamann MT, Avery M, Kelly M, Wipf P, Microbial and chemical transformation studies of the bioactive marine sesquiterpene S (+)-curcuphenol and curcudiol. Journal of Natural Products. 2002; 65:1547-1553.
34. Al-Rehaily AJ, El Sayed KA, Al-Said M, Ahmed B. Trisulcusine: a novel spiro quinazoline alkaloid from Anisotes trisulcus. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 2002; 41B:2385-2389.
33. Orabi KY, El Sayed KA, Hamann MT, Al-Said M, Higa T, Kelly M. Araguspongins K and L, New bioactive bis-1-oxaquinolizidine N-oxide alkaloids from Red Sea specimens of Xestospongia exigua (Kirkpatrick, 1900) (Demospongiae: Haplosclerida). Journal of Natural Products 2002; 65:1782-1785.
32. Hoye TR, Ayyad EN, Eklov BM, Hashish NE, Shier WT, El Sayed KA, Hamann MT. Towards computing natural product structures: 16-epi-Latrunculin B, a new stereoisomer of the potent actin polymerization inhibitor, latrunculin B. Journal of American Chemical Society, 2002; 124:7405-7410.
31. El Sayed KA, Dunbar DC. Microbial transformation of rubijervine. Chemical and Pharmaceutical Bulletin 2002; 50:1427-1429.
30. Yousaf M, El Sayed KA, Rao KV, Lim CW, Hu J, Kelly M, Franzblau SG, Zhang F, Peraud O, Hill RT, Hamann MT. 12,34-Oxamanzamines, novel biocatalytic and natural products from manzamine producing Indo-Pacific sponges. Tetrahedron 2002; 58:7397-7402.
29. Hamann MT, El Sayed KA. Methods of treating drug-resistant infections through administration of pharmaceutical compositions comprising manzamine alkaloids. PCT Int. Appl. 2002; Application: WO2001-2001US27035 200110829. AN 2002:171687.
28. El Sayed KA, Orabi KY, Dunbar DC, Hamann MT, Avery MA, Sabnis YA, Mossa JS, El-Feraly FS. Transformation of lactone to lactam in sarcophine and antimalarial activity of the resulting N-substituted azasarcophines. Tetrahedron 2002; 58:3699-3708.
27. El Sayed KA, Dunbar DC, Kelly M, Kara UAK, Ang KH, Katsuyama I, Hamann MT. New manzamine alkaloids with potent activity against infectious diseases. Journal of American Chemical Society 2001;123:1804-1808.
26. El Sayed KA, Hamann MT, Hashish NE, Shier T, Kelly M, Khan A. Antimalarial, antiviral, and antitoxoplasmosis norsesterterpene peroxide acids from the Red Sea sponge Diacarnus erythraeanus. Journal of Natural Products 2001; 64:522-524.
25. El Sayed KA. A pseudoguaiane sesquiterpene xylopyranoside from Echinops hussoni. Die Pharmazie, 2001; 56: 415-417.
24. El Sayed KA. Microbial transformation of hypoestenone. Journal of Natural Products, 2001; 64: 373-375.
23. El Sayed KA, Bartyzel P, Dunbar DC, Shen X, Wilkins SP, Perry TL, Zjawiony JK, Hamann MT. Marine natural products as antituberculosis agents. Tetrahedron, 2000; 56:949-953.
22. El Sayed KA, Ross SA, El Sohly MA, Khalafalla MM, Abdel-Halim OB, Ikegami F. Effects of different levels of fertilizers on the amino acid, fatty acid and essential oil composition of Nigella sativa L. seeds. Saudi Pharmaceutical Journal, 2000; 8:175-182.
21. Ilias M, El Sayed KA, Mossa J, Al-Said M, El-Feraly FS, Clark AM, Hufford CD, Oh S, Mayer AMS. Bioactive 12-oleanene triterpene and secotriterpene acids from Maytenus undata. Journal of Natural Products, 2000; 63:605-610.
20. El Sayed KA. Microbial transformation of papaveraldine, Phytochemistry 2000; 53:675-678.
19. El Sayed KA. Microbial models of mammalian metabolism. Microbial transformation of naproxen. Die Pharmazie 2000; 55:934-936.
18. Orabi KY, El Sayed KA, Al-Said M, El-Feraly FS. Sesquiterpene lactones from Onopordium ambiguum. Saudi Pharmaceutical Journal 2000; 8:101-105.
17. El Sayed KA, Al-Said M, El-Feraly FS, Ross SA. Quinoline alkaloids from Ruta chalepensis. Journal of Natural Products, 2000; 63:995-997.
16. El Sayed KA, Dunbar DC, McChesney JD, Zaghloul AM, Halim AF. Transformation of jervine by Cunninghamell a elegans 9245. Phytochemistry 2000; 55: 19-22.
15. El Sayed KA, Hamann MT, Mayer AMS, Kelly M. The biocatalytic transformation of furan to amide in the bioactive marine natural product palinurin, Journal of Organic Chemistry. 1999; 64:9258-9260.
14. Cutler HG, Cutler SJ, Ross SA, El Sayed KA, Dugan FM, Bartlett MG, Hill AA, Hill RA, Parker SR. Koninginin G, a new metabolite from Trichoderma aureoviride. Journal of Natural Products, 1999; 62: 137-139.
13. El Sayed KA, Hamann MT, Waddling CA, Jensen C, Lee SK, Dunstan CA, Pezzuto JM. Structurally novel bioconversion products of the marine natural product sarcophine effectively inhibit JB6 celltransformation. Journal of Organic Chemistry, 1998; 63: 7449-7455.
12. El Sayed KA, Microbial biotransformation of veratramine. Journal of Natural Products 1998; 61:149-151.
11. El Sayed KA, Hamann MT, Abd El-Fattah H, Zaghloul A M. New pyrrole alkaloids from Solanum sodomaeum L. Journal of Natural Products 1998; 61:848-850.
10. Ross SA, El Sayed KA, El Sohly MA, Hamann MT, Abdel-Halim, OB, Ahmed AF, Ahmed MM. Phytochemical analysis of Geigeria alata and Francoueuria crispa essential oils. Planta Medica 1997; 63: 479-482.
9. El Sayed KA, Dunbar DC, Perry TL, Wilkins SP, Hamann MT, Greenplate JT, Miller-Wideman M. Marine natural products as prototype insecticidal agents. Journal of Agriculture and Food Chemistry,1997; 45:2735-2739.
8. El Sayed KA, McChesney JD, Halim AF, Zaghloul AM, Lee I. A study of alkaloids in Veratrum viride. International J. Pharmacognosy 1996; 34:161-173.
7. El Sayed KA, Hamann MT. A new norcembranoid dimer from the Red Sea soft coral Sinularia gardineri. Journal of Natural Products, 1996; 59: 687-689.
6. El Sayed KA, Dunbar DC, Goins DK, Cordova CR, Perry TL, Wesson KJ, Sanders SC, Janus SA, Hamann MT. The marine environment: A resource for prototype antimalarial agents. Journal ofNatural Toxins, 1996; 5:261-285.
5. El Sayed KA, Halim AF, Zaghloul AM, McChesney JD, Stone MP, Voehler M, Hayashi K. Pregnane glycosides from Stapelia variegata L. Phytochemistry 1995; 39:395-403.
4. El Sayed KA, McChesney JD, Halim AF, Zaghloul AM, Voehler M. Two steroidal alkaloids from Veratrum viride. Phytochemistry 1995; 38:1547-50.
3. Badria FA, McChesney JD, Halim AF, Zaghloul AM, El Sayed KA. Time course and inhibition of stavaroside K, veratarmine and cevine-induced hemolysis by other pregnane glycosides and Veratrum alkaloids. Die Pharmazie 1995; 50:421-23.
2. El Sayed KA, Halim AF, Zaghloul AM, Voehler M. First report of sarcostin isolation from Cynanchum acutum L.(Asclepiadaceae). Fac. Sci. Proc.CCRD'94, 1994;6N/1-6N/4, Mansoura Univ., Egypt.
1. Halim AF, Zaghloul AM, El Sayed KA. Lupeol long-chain fatty acid esters and other lipid constituents from Cynanchum acutum L. (Asclepiadaceae). Egyptian J. Pharm. Sci. 1990; 31: 99-101.

Paper Presentations

158. Heba Elsayed, Eman Haggag, Amel Kamal, Hassan Ebrahim, Khalid El Sayed. Plants ultivated in Egypt as a source of new breast cancer migration inhibitors. The 40th Annual MALTO, Medicinal Chemistry-Pharmacognosy, Meeting-in-Miniature, Little Rock, AR, May 19-21, 2013
157. Mohamed Mohyeldin, Belnaser Busnena, Khalid El Sayed. Optimization of standardized extra-virgin olive oil secoiridoid rich fractions as new dietary-based c-Met inhibitors for the control of metastatic breast malignancies. The 40th Annual MALTO, Medicinal Chemistry-Pharmacognosy, Meeting-in-Miniature, Little Rock, AR, May 19-21, 2013
156. Hassan Ebrahim and Khalid El Sayed. Antimigratory secondary metabolites from the terrestrial fungus Aspergillus terreus. The 40th Annual MALTO, Medicinal Chemistry-Pharmacognosy, Meeting-in-Miniature, Little Rock, AR, May 19-21, 2013
155. Belnaser Busnena, Khalid El Sayed. Olive secoiridoids and semisynthetic bioisostere analogues for the control of metastatic breast cancer. The 40th Annual MALTO, Medicinal Chemistry-Pharmacognosy, Meeting-in-Miniature, Little Rock, AR, May 19-21, 2013
154. Ahmed Foudah, Khalid El Sayed. Optimization of the marine natural product sipholenols as inhibitors of breast cancer proliferation and migration. The 40th Annual MALTO, Medicinal Chemistry-Pharmacognosy, Meeting-in-Miniature, Little Rock, AR, May 19-21, 2013
153. Ananthula S, Parajuli P, Akl M, Behery F, Ayoubi A, El Sayed K, Nazzal S, Sylvester P. Oxazine derivatives of γ-tocotrienol display potent anticancer effects in vivo. The 13th ULM-2013 Student Research Symposium, February 19, 2013,Monroe, Louisiana
152. Al Suliman R, El Sayed KA, Bednar JA, Meyer SA. Comparison of MNX (Hexahydro-1- nitroso-3, 5-dinitro-1, 3, 5-triazine) with RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) metabolism by rat liver microsomal and S9 fractions. The 13th ULM-2013 Student Research Symposium, February 19, 2013,Monroe, Louisiana
151. Meyer SA, Jaligama S, El Sayed KA, Dugas T. Different toxicity outcomes in rats correlated with EPR and NMR spectra of crude oil from different sources. Society of Toxicology 52nd Annual Meeting, March 10-14, 2013, San Antonio, Texas
150. Sallam A, Ayoub N, Gisennadaner C, Meyer S, El Sayed KA. Optimization of the mycotoxin indole diterpene alkaloids as anticancer agents. 2012 AAPS Annual Meeting and Exposition, Oct 14-17, 2012. Chicago, IL
149. Abuznait A, Qosa H, Sylvester PW, El Sayed K, Kaddoumi A. Induction of Expression and Functional Activity of P-glycoprotein Efflux Transporter by Diverse Natural Products. 2012 AAPS Annual Meeting and Exposition., Oct 14-17, 2012. Chicago, IL
148. Belnaser Busnena, Tina Melancon, Khalid El Sayed. Optimization of olive oil phenolics as breast cancer migration inhibitors. Design and synthesis of antimigratory tyrosol esters and carbamates. Thirty-Ninth Annual MALTO, Medicinal Chemistry-Pharmacognosy, Meeting-in-Miniature, ULM-Monroe, LA, May 20-22, 2012
147. Ahmed Foudah, Sandeep Jain, Khalid El Sayed. Optimization of the marine natural product sipholenols as inhibitors of breast cancer migration. Thirty-Ninth Annual MALTO, Medicinal Chemistry-Pharmacognosy, Meeting-in-Miniature, ULM-Monroe, LA, May 20-22, 2012
146. Fathy Behery, Mohamed Akl, Suryatheja Ananthula, Parash Parajuli, Paul Sylvester, Khalid El Sayed. Tocotrienol electrophilic substitution products as breast cancer proliferation and migration inhibitory leads. Thirty-Ninth Annual MALTO, Medicinal Chemistry-Pharmacognosy, Meeting-in-Miniature, ULM-Monroe, LA, May 20-22, 2012
145. Asmaa Sallam, Nehad Ayoub, Sharon Meyer, Christopher Gissendanner, Paul Sylvester, Khalid El Sayed. The mycotoxin indole diterpene alkaloid penitrems as novel scaffolds for development of new anticancer agents. Thirty-Ninth Annual MALTO, Medicinal Chemistry-Pharmacognosy, Meeting-in-Miniature, ULM-Monroe, LA, May 20-22, 2012
144. Belnaser Busnena, Tina Melancon, Khalid El Sayed. Optimization of the olive oil phenolics as breast cancer migration inhibitors. Design and synthesis of antimigratory ester and carbamate analogues of tyrosol. The 12th ULM-2012 Student Research Symposium, April 25, 2012,Monroe, Louisiana
143. Asmaa Sallam, Nehad Ayoub, Sharon A. Meyer, Christopher Gissendanner, Paul Sylvester, Khalid El Sayed. Discovery and optimization of the mycotoxin indole diterpene alkaloid penitrems as novel inhibitors of breast cancer proliferation and migration. The 12th ULM-2012 Student Research Symposium, April 25, 2012,Monroe, Louisiana
142. Fathy Behery, Mohamed Akl, Suryatheja Ananthula, Parash Parajuli, Paul Sylvester, Khalid El Sayed. Tocotrienol electrophilic substitution products as breast cancer proliferation and migration inhibitory leads. The 12th ULM-2012 Student Research Symposium, April 25, 2012,Monroe, Louisiana
141. Ahmed Foudah, Sandeep Jain, Khalid El Sayed. Optimization of the marine natural product sipholenols as inhibitors of breast cancer migration. The 12th ULM-2012 Student Research Symposium, April 25, 2012,Monroe, Louisiana
140. El Sayed KA, Elnagar KY, Khanfar M. Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c-Met inhibitor and optimization of Veratrum alkaloids as Hedgehog signaling inhibitors. American Association for Cancer Research 103th Annual Meeting, March 31-April 3, 2012, Chicago, Illinois
139. Jaligama S, El Sayed KA, Meyer SA. Crude oil from various sources yield different acute toxicity outcomes in rats: Correlation with 1H NMR and EPR spectra. Society of Toxicology 51st Annual Meeting, March 11-15, 2012, San Francisco, California
138. Eterović VA, Del Valle-Rodriguez1 A, Pérez D, El Sayed KA, Ferchmin PA.A structure-activity study of 4R-cembranoid reversal of diisopropylfluorophosphate-inflicted functional impairment in hippocampal slices. Neuroscience 2011, November 12-16, 2011, Washington DC
137. Sallam AA, El Sayed KA. Discovery and optimization of the marine-derived indole diterpene alkaloid penitrems as potential anticancer scaffolds. The AAPS Annual Meeting, November 14-18, 2011, Washington, DC
136. Orabi KY, Abaza MS, El Sayed KA, Elnagar AY, Al-Attiyah R, Guleri RP. Syringic acid derivatives as proteasome inhibitors. The Annual Meeting of the American Society of Pharmacognosy, July 30-August 4, 2011, San Diego, California
135. Abuznait AH, El Sayed KA, Kaddoumi A. In vitro induction of P-glycoprotein and LRP1 expression and functional activity following exposure to olive oil-derived oleocanthal: Potential role in amyloid-beta clearance. 11th ULM-2011 Student Research Symposium, May 5, 2011,Monroe, Louisiana
134. Sallam AA, El Sayed KA. Penitrems: Marine-derived indole diterpene alkaloids as potential anticancer candidates. 11th ULM-2011 Student Research Symposium, May 5, 2011,Monroe, Louisiana
133. Behery FA, Asmaa A. Sallam, El Sayed KA. Antiproliferative and antimigratory 3,4-dihydro-1,3-oxazine, Mannich base, and hydroxymethyl analogues of the marine phenolic sesquiterpene (S)-(+)-curcuphenol. 11th ULM-2011 Student Research Symposium, May 5, 2011,Monroe, Louisiana
132. Foudah AI, El Sayed KA. Endophytic fungi associated with the bald cypress tree (Taxodium distichum) as producers for novel inhibitors of prostate and breast cancer migration and invasion. 11th ULM-2011 Student Research Symposium, May 5, 2011,Monroe, Louisiana
131. Busnena BA, Sallam A, El Sayed KA. Assessment and optimization of olive oil secoiridoids as prostate cancer migration inhibitors. 11th ULM-2011 Student Research Symposium, May 5, 2011,Monroe, Louisiana
130. Youssef R, Sallam A, McCoole M, Baer K, Kaddoumi A, El Sayed KA. Metabolism of the Ca-dependent K-channel inhibitor penitrem A in catfish and microbial models. 11th ULM-2011 Student Research Symposium, May 5, 2011,Monroe, Louisiana
129. Behery F, Sylvester PW, El Sayed KA. Semisynthetic optimization of tocotrienols as breast cancer proliferation and migration inhibitors. 85th Annual Meeting of Louisiana Academy of Science, February 26, 2010, Monroe, Louisiana
128. Sallam AA, Sindhura Ramasahayam, Sharon A. Meyer, El Sayed KA. Design, synthesis, and biological evaluation of dibromotyrosine analogues inspired by marine natural products as inhibitors of human prostate cancer proliferation, invasion, and migration. 85th Annual Meeting of Louisiana Academy of Science, February 26, 2010, Monroe, Louisiana
127. Abuznait A, Qosa H, El Sayed KA, Kaddoumi A. Induction of Expression and Functional Activity of P-glycoprotein Efflux transporter by diverse natural products. 85th Annual Meeting of Louisiana Academy of Science, February 26, 2010, Monroe, Louisiana
126. Sallam AA, Sindhura Ramasahayam, Sharon A. Meyer, El Sayed KA. Design, synthesis, and biological evaluation of dibromotyrosine analogues inspired by marine natural products as inhibitors of human prostate cancer proliferation, invasion, and migration. The AAPS Annual Meeting, November 14-18, 2010, New Orleans, Louisiana
125. Khanfar MA, Hill R, Kaddoumi A, El Sayed K. Computer-assisted discovery, design, synthesis, in vitro, and in vivo Evaluations of highly potent and selective inhibitors of glycogen Synthase kinase-3β. The AAPS Annual Meeting, November 14-18, 2010, New Orleans, Louisiana
124. Ahmed Y. Elnagar, Mohammad A. Khanfar, Paul W. Sylvester, Khalid A. El Sayed. Computer-Assisted Identification of Oleocanthal as a Potent c-Met Inhibitor for the Control of Metastatic Breast and Prostate Cancers. The ULM 10th Student Research Symposium, April 2010, Monroe, Louisiana
123. Mohammad Khanfar, Mudit Mudit, Bilal Abuasal, Ronald Hill, Amal Kaddoumi, Khalid El Sayed. Computer-assisted discovery, design, synthesis, in vitro, and in vivo evaluations of highly potent and selective inhibitors of glycogen synthase kinase-3β. The ULM 10th Student Research Symposium, April 2010, Monroe, Louisiana
122. Asmaa Sallam, Khalid El Sayed. Rational design of verongiaquinol-inspired bromotyrosine analogues as prostate cancer proliferation and migration inhibitors. The ULM 10th Student Research Symposium, April 2010, Monroe, Louisiana
121. Fathy Behery, Ahmed Elnagar, Vikram Wali, Paul Sylvester, Khalid El Sayed. Redox-Silent Tocotrienol Esters as Breast Cancer Proliferation and Migration Inhibitors.The ULM 10th Student Research Symposium, April 2010, Monroe, Louisiana
120. Hossam Hassan, Mohammad Khanfar, Ahmed Elnagar, Rabab Mohamed, Lamiaa Shaala, Diaa Youssef, Mohamed Hifnawy, Khalid El Sayed. Eunicellin-based diterpenoids from the Red Sea soft coral Cladiella pachyclados as prostate and breast cancers migration and proliferation inhibitors. The ULM 10th Student Research Symposium, April 2010, Monroe, Louisiana
119. Mudit. Mudit,Khalid El Sayed. Optimization of phenylmethylene hydantoins as prostate cancer migration inhibitor scaffolds. The ULM 10th Student Research Symposium, April 2010, Monroe, Louisiana
118. Fathy Behery, Ahmed Elnagar, Vikram Wali, Paul Sylvester, Khalid El Sayed. Redox-silent tocotrienol esters as breast cancer proliferation and migration inhibitors. The 37th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 23-25, 2010, Oxford, Mississippi
117. Asmaa Sallam, El Sayed K. Antiproliferative and anti-migratory effects of verongiaquinol-inspired bromotyrosine analogues against human prostate cancer: Design, synthesis, and biological evaluations. The 37th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 23-25, 2010, Oxford, Mississippi
116. Abdel Bar F, Khanfar M, Liu H, Raisch K, Zaghloul A, Badria F, Sylvester P, Ahmed K, El Sayed K. Rationale design and semisynthesis of novel betulinic acid analogues as potent topoisomerase I inhibitors. The ULM 9th Student Research Symposium, April 2009, Monroe, Louisiana.
115. Sallam A, Ramasahayam S, Meyer S, El Sayed K. Rational design, synthesis, and biological evaluations of antileukemic/anti-invasive bromotyrosine derivatives inspired by the marine natural product verongiaquinol. The ULM 9th Student Research Symposium, April 2009, Monroe, Louisiana
114. Behery F, Sylvester P, El Sayed K. Toward the identification of molecular target(s): Preparation of fluorescent tocotrienol analogues. The ULM 9th Student Research Symposium, April 2009, Monroe, Louisiana
113. Mudit M, Khanfar M, Muralidharan A, Thomas S, Shah G, El Sayed K. Phenylmethylene hydantoins and their anti-metastatic potential against advanced prostate cancer. The ULM 9th Student Research Symposium, April 2009, Monroe, Louisiana
112. Khanfar M, Youssef D, El Sayed K. Rationale design of semisynthetic latrunculin analogues as inhibitors for metastatic cancer, preliminary structure-activity relationship, and 3D QSAR studies. The ULM 9th Student Research Symposium, April 2009, Monroe, Louisiana
111. Hassan H, Elnagar A, Abdel-Salam R, Shaala L, Youssef D, Hifnawy M, El Sayed K. Bioactive Eunicelline-based diterpenoids from the Red Sea soft coral Caldiella sp. The ULM 9th Student Research Symposium, April 2009, Monroe, Louisiana
110. Elnagar A, Wali V, Sylvester P, El Sayed K. Rationally-designed tocotrienol analogues with enhanced antiproliferative activity. The ULM 9th Student Research Symposium, April 2009, Monroe, Louisiana
109. Behery F, Sylvester P, El Sayed K. Toward the identification of molecular target(s): Preparation of fluorescent tocotrienol analogues. The 36th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 17-19, 2009, Memphis, Tennessee
108. Mudit M, Khanfar M, Muralidharan A, Thomas S, Shah G, El Sayed K. Phenylmethylene hydantoins and their anti-metastatic potential against advanced prostate cancer. The 36th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 17-19, 2009, Memphis, Tennessee
107. Khanfar M, Youssef D, El Sayed K. Rationale design of semisynthetic latrunculin analogues as inhibitors for metastatic cancer, preliminary structure-activity relationship, and 3D QSAR studies. The 36th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 17-19, 2009, Memphis, Tennessee
106. Hassan H, Elnagar A, Abdel-Salam R, Shaala L, Youssef D, Hifnawy M, El Sayed K. Bioactive Eunicelline-based diterpenoids from the Red Sea soft coral Caldiella sp. The 36th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 17-19, 2009, Memphis, Tennessee
105. Elnagar A, Wali V, Sylvester P, El Sayed K. Rationally-designed tocotrienol analogues with enhanced antiproliferative activity. The 36th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 17-19, 2009, Memphis, Tennessee
104. Abraham I, Jain S, Wu CP, Kuang Y, Lee J, Chen X, El Sayed KA, Ambudkar SV, Chen ZS. Marine-derived sipholane triterpenes reverse P-gp-mediated MDR in cancer cells. American Association for Cancer Research 100th Annual Meeting, April 18-22, 2009, Denver, Colorado
103. Shah GV, Muralidharan A, Shibu T, Mudit M, Khanfar M, El Sayed KA. Identification of a small molecule(s) class to augment cell-cell adhesion and attenuate prostate tumor growth and metastasis. American Association for Cancer Research 100th Annual Meeting, April 18-22, 2009, Denver, Colorado
102. Orabi A, Wali VB, Sylvester P, El Sayed KA. Rationally designed Tocotrienol analogues in order to enhance their antiproliferative activity. International Congress on Natural Products Research, August 1-5, 2008, Athens, Greece
101. Sandeep Jain, Zhi Shi, Zhe-Sheng Chen, Khalid El Sayed. Bioactive triterpenoids from the Red Sea sponge Callyspongia siphonella. The 35th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 18-20, 2008, Little Rock, Arkansas
100. Mudit Mudit, Mohamed Khanfar, Bhushan Awate, Girish Shah, Khalid El Sayed. Novel marine-derived leads for metastatic prostate cancer. The 35th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 18-20, 2008, Little Rock, Arkansas
99. Ahmed Y. Orabi, Vikram B. Wali, Paul W. Sylvester, Khalid El Sayed. Rationally-designed tocotrienol analogues with enhanced antiproliferative activity. The 35th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 18-20, 2008, Little Rock, Arkansas
98. Fatma M. Abdel Bar, Ahmed M. Zaghloul, Sunita V. Bachawal, Paul W. Sylvester, Kadria F. Mohamed, Khalid El Sayed. Antiproliferative Triterpenes from Melaleuca ericifolia. The 35th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 18-20, 2008, Little Rock, Arkansas
97. Mohammad A. Khanfar, A. Muralidharan, Bhushan Awate, Diaa T.A. Youssef, Girish Shah, Khalid El Sayed. Latrunculin A and its C-17-O-carbamates as potent anti-invasive Prostate cancer leads. The 35th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 18-20, 2008, Little Rock, Arkansas
96. Asmaa Sallam, Frederic Rainey, Khalid El Sayed. Secondary Metabolites from the Symbiotic Marine Bacterium Bacillus pumilus. The 35th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 18-20, 2008, Little Rock, Arkansas
95. Mohamed Khanfar, Mudit Mudit, Bhushan Awate, Girish Shah, Khalid El Sayed. Computer-assisted design of novel inhibitors for metastatic prostate cancer. ULM 8th Student Research Symposium, Monroe, April 2008, Monroe, Louisiana
94. Mudit Mudit, Mohamed Khanfar, Bhushan Awate, Girish Shah, Khalid El Sayed. Novel marine-derived leads for metastatic prostate cancer. ULM 8th Student Research Symposium, April 2008, Monroe, Louisiana
93. Ahmed Y. Orabi, Vikram B. Wali, Paul W. Sylvester, Khalid A. El Sayed. Rationally-designed tocotrienol analogues with enhanced antiproliferative activity. ULM 8th Student Research Symposium, April 2008, Monroe, Louisiana
92. Dalia Abdelhalim, Hany Baraka, Mohamed Khanfar, Ahmed Orabi, Girish Shah, Khalid El Sayed. Rationale-design of anti-invasive 4-O-methyl-2,7,11-cembratriene-4-6-diol.ULM 8th Student Research Symposium, April 2008, Monroe, Louisiana
91. Asmaa Sallam, Frederick Rainey, Khalid El Sayed. Secondary Metabolites from the Symbiotic Marine Bacterium Bacillus pumilus. ULM 8th Student Research Symposium, April 2008, Monroe, Louisiana
90. Sandeep Jain, Zhe-Sheng Chen, Paul W. Sylvester, Khalid El Sayed. Bioactive triterpenoids from the Red Sea sponge Callyspongia siphonella. ULM 8th Student Research Symposium, April 2008, Monroe, Louisiana
89. Fatma M. Abdel Bar, Ahmed M. Zaghloul, Sunita V. Bachawal, Paul W. Sylvester, Kadria F. Mohamed, Khalid A. El Sayed. Antiproliferative Triterpenes from Melaleuca ericifolia. ULM 8th Student Research Symposium, April 2008, Monroe, Louisiana
88. El Sayed Khalid, Khanfar Mohamed, Muralidharan A., Awate Bhushan,Youssef Diaa, Girish Shah. Targeting cytoskeleton signaling in cancer: Rationale design of semisynthetic latrunculin analogs as inhibitors for metastatic prostate cancer. American Association for Cancer Research Annual Meeting, April 12-16, 2008, Los Angeles California
87. El Sayed Khalid, Khanfar Mohamed, Muralidharan A., Awate Bhushan, Youssef Diaa, Girish Shah. Targeting cytoskeleton signaling in cancer: Rationale design of semisynthetic latrunculin analogs as inhibitors for metastatic prostate cancer. American Association for Cancer Research Annual Meeting, April 12-16, 2008, Los Angeles California
86. Mohamed Khanfar, Mudit Mudit, Bhushan Awate, Girish Shah, Khalid El Sayed. Computer-Assisted Design of Novel Inhibitors for Metastatic Prostate Cancer. 6th Louisiana Biomedical Research Network Meeting, January 25-27, 2008, New Orleans , Louisiana
85. Mudit Mudit, Mohamed Khanfar, Bhushan Awate, Girish Shah, Khalid El Sayed. Optimization of Novel. Marine-Derived Leads as Potential Treatment for Metastatic Prostate Cancer. 6th Louisiana Biomedical Research Network Meeting, January 25-27, 2008, New Orleans , Louisiana
84. Sandeep Jain, Zhi-shi, Zhe-Sheng Chen, Khalid El Sayed. Bioactive Sipholane Triterpenoids from the Red Sea Sponge Callyspongia siphonella.6th Louisiana Biomedical Research Network Meeting, January 25-27, 2008, New Orleans, Louisiana
83. Hany Baraka, John Williams, Bhushan Awate, Girish Shah, Khalid El Sayed. Anti-invasive Diterpenes for Treatment of Metastatic Prostate Cancer. 6th Louisiana Biomedical Research Network Meeting, January 25-27, 2008, New Orleans , Louisiana
82. Khalid El Sayed, Mohamed Khanfar, Mudit Mudit, Hany Baraka, Bhushan Awate, Girish Shah.Discovery, Design, Synthesis, and Development of New Leads for Treatment of Metastatic Prostate Cancer Inspired by Marine Natural Products. 6th Louisiana Biomedical Research Network Meeting, January 25-27, 2008, New Orleans, Louisiana
81. Sandeep Jain, Zhi Shi, Zhe-Sheng Chen, Khalid El Sayed. Reversal of P-glycoprotein-mediated multidrug resistance by sipholane triterpenoids. 48th Annual Meeting of the American Society of Pharmacognosy, July 14-18, 2007, Portland, Maine
80. Mudit Mudit, Anbalagan Muralidharan, Shibu Thomas, Girish Shah, Khalid El Sayed. Isolation and synthesis of potential lead compounds from the Red Sea sponge Hemimycale arabica. 48th Annual Meeting of the American Society of Pharmacognosy, July 14-18, 2007, Portland, Maine
79. Ahmed Orabi, Paul Sylvester, Vikram Wali, Khalid El Sayed. Biocatalytic studies of the anticancer palm oil tocotrienols and tocopherols. 48th Annual Meeting of the American Society of Pharmacognosy, July 14-18, 2007, Portland, Maine
78. Hassan Shallal, Paige Newman, Anbalagan Muralidharan, Shibu Thomas, Girish Shah, Diaa Youssef, Khalid
El Sayed. Semisynthetic optimization of the anti-invasive marine macrolide latrunculins. The 34th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 20-22, 2007, Monroe, Louisiana
77. Mudit Mudit, Anbalagan Muralidharan, Shibu Thomas, Girish Shah, Khalid El Sayed. Isolation and structure-activity relationship study of the marine-derived phenylmethylenehydantoins. The 34th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 20-22, 2007, Monroe, Louisiana
76. Sandeep Jain, Zhi Shi, Zhe-Sheng Chen, Khalid El Sayed. Reversal of P-glycoprotein-mediated multidrug resistance by sipholane triterpenoids. The 34th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 20-22, 2007, Monroe, Louisiana
75. Ahmed Orabi, Paul Sylvester, Vikram Wali, Khalid El Sayed. Chemistry and pharmacology of palm oil tocotrienol rich fraction. The 34th Annual MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 20-22, 2007, Monroe, Louisiana
74. Sandeep Jain, Amit Shirode, Ashley Barbo, Zhi Shi, Zhe-Sheng Chen, Diaa T.A. Youssef, Paul Sylvester, Khalid El Sayed. Anticancer potential of sipholane triterpenoids from the marine sponge Callyspongia siphonella. ULM 7th Annual Student Research Symposium. April 18, 2007, Monroe, Louisiana
73. Mudit Mudit, Anbalagan Muralidharan, Shibu Thomas, Girish Shah, Khalid El Sayed. Anti-invasive hydantoins from the Red Sea sponge Hemimycale arabica. ULM 7th Annual Student Research Symposium. April 18, 2007, Monroe, Louisiana
72. Shi Z, Jain S, Kim I, Peng XX, Abraham I, Fu L, Youssef DTA, El Sayed KA, Ambudkar S, Chen ZS. Sipholenol A, a marine-derived sipholane triterpene, potently reverse P-glycoprotein mediated MDR in cancer cells. American Association for Cancer Research Annual Meeting, April 14-18, 2007, Los Angeles California
71. El Sayed KA, Shallal H, Mudit M, Prestridge J, A. Muralidharan, Thomas S, Shah G. Marine natural products are potential source for novel drugs for the treatment of metastatic prostate cancer. American Association for Cancer Research Annual Meeting, April 14-18, 2007, Los Angeles California
70. Mudit M, Prestridge J, A. Muralidharan, Thomas S, Shah G, El Sayed K. Anti-invasive hydantoins from the Red Sea sponge Hemimycale Arabica. 5th Louisiana Biomedical Research Network Meeting, January 26-28, 2007, Bossier City, Louisiana
69. El Sayed KA. Anticancer marine natural products. 5th Louisiana Biomedical Research Network Meeting, January 26-28, 2007, Bossier City, Louisiana
68. El Sayed KA. Anti-invasive and antiangiogenic marine natural products. First Kuwait Pharmaceutical Sciences Annual Meeting , Kuwait , December 11-14, 2006, Kuwait (Invited Keynote Speaker)
67. S Laphookhieo, I Famakinwa, M Yousaf, A Shirode, V Wali, P Sylvester and K El Sayed. Biocatalytic and semisynthetic optimization of the anticancer tobacco cembranoids. Annual Meeting South Central Chapter of the Society of Toxicology, October 12-13, 2006, Monroe, Louisiana
66. S. Jain, A. Barbo, S. Yacoub, A. Shirode, K.A. El Sayed, and P.W. Sylvester. Biocatalytic study of bioactive marine natural products: Triterpenoid sipholanes. Annual Meeting South Central Chapter of the Society of Toxicology, October 12-13, 2006, Monroe, Louisiana
65. H Shallal, K El Sayed. Computer-assisted design of anticancer marine macrolide latrunculins. Annual Meeting South Central Chapter of the Society of Toxicology, October 12-13, 2006, Monroe, Louisiana
64. Sawant, S., Youssef, D., Sylvester, S., Marchetti, D., El Sayed, K. Towards optimizing anticancer terpenes from the Red Sea Soft Coral Sarcophyton glaucum. 47th Annual Meeting of the American Society of Pharmacognosy, August 5-9, 2006, Arlington, Virginia
63. El Sayed, K., Yousaf, M., Prestridge, J., Sawant, S., Wali, V., Sylvester, P., Steffen, R., Mueller, W. Biocatalytic and semisynthetic studies of anticancer tobacco cembranoids. 47th Annual Meeting of the American Society of Pharmacognosy, August 5-9, 2006, Arlington, Virginia
62. Jain, S., Barbo, A., Youssef, D., El Sayed, K.  Chemical and biocatalytic transformation studies of the Bioactive Marine-Derived triterpenoid sipholanes. North Louisiana Partnership for Innovation Regional Research Day, Shreveport , Louisiana , May 1, 2006
61. Sawant, S., Youssef, D., Sylvester, S., Marchetti, D., El Sayed, K. Towards optimizing anticancer terpenes from the Red Sea Soft Coral Sarcophyton glaucum North Louisiana Partnership for Innovation Regional Research Day, Shreveport, Louisiana, May 1, 2006
60. El Sayed, K., Phadnis, A., Yousaf, M., Prestridge, J., Sawant, S., Wali, V., Sylvester P. Biocatalytic and semisynthetic studies of anticancer tobacco cembranoids. North Louisiana Partnership for Innovation Regional Research Day, Shreveport , Louisiana , May 1, 2006
59. Sawant, S., Youssef, D., Sylvester, S., Marchetti, D., El Sayed, K.   Antimetastatic, Semisynthetic, and Biocatalytic Studies of Marine Cembranoids. 6th ULM Student Research Symposium, April 26, 2006
58. Barbo, A., Brode, R., Yacoub, S., Bagaley, D., Rainey, F., El Sayed, K.  A Study of the Red Sea Sponge Siphonochalina siphonella:  Biocatalysis of Sipholenol A and Bioactive Symbiotic Bacterial Secondary Metabolites. 6th ULM Student Research Symposium, April 26, 2006
57. Jain, S., Youssef, D., El Sayed, K.  Study of the Bioactive Marine Natural Products Triterpenoid Sipholanes. 6th ULM Student Research Symposium, April 26, 2006
56. Prestridge, J., Phadnis, A., Yousaf, M., Wali, V., Sylvester, P., El Sayed, K. Semisynthetic Studies of the Anticancer Tobacco Cembranoid (1S,2E,4R,6R,7E,11E)-2,7,11-Cembratriene-4,6-diol. 6th ULM Student Research Symposium, April 26, 2006
55. Prestridge, J., Yousaf, M., Wali, V., Sylvester, P., El Sayed, K., Steffen, R., Mueller, W. Semisynthetic Studies on the Anticancer Tobacco Cembranoids. North Louisiana Partnership for Innovation Regional Research Day, Shreveport , Louisiana , May 1, 2006
54. Barbo, A., Bagaley, D., Rainey, F. A., El Sayed, K.A., A study of symbiotic microorganisms associated with the Red Sea sponges Negombata magnifica and Siphonochalina siphonella.  Marine Natural Products Gordon Research Conference, February 26-March 2, 2006, Ventura, CA
53. Sawant, S., Barbo, A., Brode, R., Yousef, M., Jain, S., Youssef, D., Bagaley, D., Rainey, F., Marchetti, D.,
El Sayed, K. Novel marine-derived antibiotic and anticancer leads.  Annual Louisiana Biomedical Research Network Meeting. February 10-12, 2006.  Baton Rouge, LA
52. Bhandare, R., Mayer, A., El Sayed, K.  Synthesis and semisynthetic studies of the bioactive marine natural sesquiterpene curcuphenol.  46th Annual Meeting of the American Society of Pharmacognosy, July 2005.  Oregon State University, Corvallis, Oregon
51. Sawant, S., Sylvester, P., Avery, M., Desai, P., Youssef, D., El Sayed, K.  Semisynthetic and biocatalytic studies of cembranoids from the Red Sea soft coral Sarcophyton glaucum.  46th Annual Meeting of the American Society of Pharmacognosy.  July 2005.  Oregon State University, Corvallis, Oregon
50. El Sayed, K., Galal, A., Yacoub, S., Huntimer, E., Halaweish, F. Biocatalytic and semisynthetic optimization of the antiangiogenic and anti-inflammatory marine sipholane triterpenes.  46th Annual Meeting of the American Society of Pharmacognosy.  July 2005, Oregon State University, Corvallis, Oregon
49. Barbo, A., Sawant, S., Youssef, D., El Sayed, K. A.  Latrunculins revisited:  New natural and semisynthetic bioactive latrunculins.  46th Annual Meeting of the American Society of Pharmacognosy, July 2005.  Oregon State University, Corvallis, Oregon
48. Bhandare, R., El Sayed, K., Synthesis and semisynthetic studies of the bioactive marine natural sesquiterpene curcuphenol.  32nd MALTO Medicinal Chemistry-Pharmacognosy Meeting, Oxford, MS, May 2005
47. Sawant, S., Sylvester, P., Avery, M., Desai, P., Youssef, D., El Sayed, K. A.  Semisynthetic and biocatalytic studies of cembranoids from the Red Sea soft coral Sarcophyton glaucum.  32nd MALTO Medicinal Chemistry-Pharmacognosy Meeting, Oxford, MS, May 2005
46. Sawant, S., Sylvester, P., Avery, M., Desai, P., Youssef,  D., Mayer, A., El Sayed, K. A. Development of Bioactive Leads from the Red Sea Soft Coral Sarophyton glaucum Cembranoids.  5th Annual Student Research Symposium, ULM, Monroe, LA, April 27, 2005.  (First place winner, graduate student podium)
45. Bhandare, R., Mayer, A., El Sayed, K. A., Optimization of anti-inflammatory curcuphenols using chemical modifications.  5th Annual Student Research Symposium, ULM, Monroe, LA, April 27, 2005
44. McBride, M., McBride, T., El Sayed, K. A. Bioconversion Studies of the Bioactive Marine Sesterterpene Palinurin.  5th Annual Student Research Symposium, ULM, Monroe, LA  April 27,2005 (Second place winner, Undergraduate student poster)
43. Barbo, A., Sawant, S., Youssef, D., El Sayed, K. A.  Latrunculins revisited:  New semisynthetic bioactive latrunculins.  5th Annual Student Research Symposium, ULM, Monroe, LA  April 27, 2005 (Second place winner, Undergraduate student poster)
42. Sawant, S., Barbo, A., Bhandare, R., Sylvester, P., El Sayed, K. A.  Optimization of anticancer marine natural products using biocatalytic and semisynthetic transformations.  North Louisiana Partnership for Innovation Regional Research Day, Shreveport, LA , April 2005.
41. El Sayed, K. A., Sawant, S., Marchetti, D., Latrunculins revisited:  New natural and semisynthetic bioactive latrunculins.  LBRN, 3rd Annual Retreat, Lafayette, LA, February, 2005
40. Sawant, S., Yacoub, S., El-Malah, Y., Elnagdy, H., Sylvester, P.W., Gilbert, C., Youssef, D. T. A., Avery, M. A., Desai, P., Halaweish, F., Huntimer, E., El Sayed, K. A., 2004.  Optimization of anticancer marine natural products:  Chemical and microbial transformation studies of latrunculin B., sarcophine, and sipholane triterpenes.  International Congress on Natural Products Research, Phoenix, AZ
39. Yacoub, S., El Sayed, K. A., Halaweish, F., Huntimer, E., 2004.  Chemical and microbial transformation studies of the bioactive marine natural products sipholane triterpenes.  International Congress on Natural Products Research, Phoenix, AZ
38. Sawant, S., Sylvester, P. W., Avery, M. A., Desai, P., Youssef, D. T. A., El Sayed, K. A., 2004. Anticancer semisynthetic derivatives of cembranoid diterpene sarcophine.  International Congress on Natural Products Research, Phoenix, AZ
37. El-Malah, Y., Youssef, D. T. A., El Sayed, K. A.  Semisynthetic studies on the marine-derived macrolide latrunculin B. May 2004, 31st MALTO Medicinal Chemistry-Pharmacognosy Meeting, Memphis, TN
36. Yacoub,  S., El Sayed, K. A., Halaweish, F., Huntimer, E. Chemical and microbial transformation studies of the bioactive marine natural products sipholane triterpenes.  4th Student Research Symposium, ULM, Monroe, LA, April 2004 and 31st MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 2004, Memphis, TN
35. Elsayed, R. K., El Sayed, K. A., Rainey, F., April 2004.  Bioactive aromatic nitrogenated secondary metabolites from the marine derived bacterium Bacillus cereus.  4th Students Research Symposium, ULM, Monroe, LA and 31st MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 2004, Memphis, TN
34. Sawant, S. S.,  Sylvester, P. W., Avery, M.A., Desai, P., Youssef, D. T. A., El Sayed, K. A., April 2004.  Semisynthetic studies on the anticancer diterpene cembranoid  sarcophine.  4th Student Research Symposium.  ULM, Monroe, LA and 31st MALTO Medicinal Chemistry-Pharmacognosy Meeting, May 2004, Memphis, TN
33. Sawant, S., El Sayed, K. A., 2003. Novel bioactive halogenated and rearranged semisynthetic derivatives of the marine natural product sarcophine.  The 44th Annual Meeting of The American Society of Pharmacognosy, and Monroe Wall Symposium, Chapel Hill, North Carolina
32. Sawant, S., Yacoub, S., El Sayed, K. A., 2003. Toward enhancing natural products structure and bioactivity ranges:  Semisynthetic studies of the marine natural products sarcophine and uncarine c and mitraphylline, the major Cat's Claw alkaloids.  The 44th Annual Meeting of The American Society of Pharmacognosy, and Monroe Wall Symposium, Chapel Hill, North Carolina
31. Yacoub, S., El Sayed, K. A., 2003. "Chemical transformation studies of mitraphylline and uncarine C, the major Cat's Claw alkaloids".  30th MALTO Medicinal Chemistry-Pharmacognosy Meeting, Little Rock, Arkansas
30. Miller, J., Sylvester, P., El Sayed, K. A., 2003. "Biocatalysis studies of palm oil a-tocopherol and a-tocotrienol".  30th MALTO Medicinal Chemistry-Pharmacognosy Meeting.  Little Rock, Arkansas
29. Sawant, S., El Sayed, K. A., 2003.  "Halogenation of the bioactive marine natural product sarcophine." 30th MALTO Medicinal Chemistry-Pharmacognosy Meeting, Little Rock, Arkansas
28. El Sayed, K. A., and Orabi, K. Y., 2002. "Microbial Biocatalysis as an Efficient Tool to Generate Novel Natural Products." The 43rd Annual Meeting of The American Society of Pharmacognosy and Monroe Wall Symposium, New Brunswick, New Jersey
27. Yacoub, S., and El Sayed, K. A., 2002.  "Microbial Biocatalysis of Uncarine E, The Major Cat's Claw (Uncaria tomentosa) Alkaloid and Zingiberene of Ginger (Zingiber officinal)".  29th MALTO Medicinal Chemistry-Pharmacognosy Meeting at Monroe, Louisiana
26. El Sayed, K. A., Orabi, K. Y., Dunbar, D. C., El-Feraly, F. S., Avery, M. and Hamann, M. T., 2001. "Transformation of Lactone to Amide in Sarcophine and Antimalarial Activity of The Resutling N-Containing Cembranoids."  The 42nd American Society of Pharmacognosy Annual Meeting, Oaxaca, Mexico
25. El Sayed, K. A., Hamann, M. T., and Avery, M., 2001.  "Microbial Transformation of S (+) - Curcuphenol and Curcudiol".  28th MALTO Medicinal Chemistry-Pharmacognosy Meeting at Oxford, Mississippi.
24. El Sayed, K. A., Wilkins, S. P., Burkepile, D. E., Kelly, M., Ang, K. K. H., Kara, U. A. K., and Hamann, M. T., 2000.  Marine natural products with activity against infectious diseases and their optimization using biocatalysis and parallel synthesis.  Marine National Products Gordon Conference
23. El Sayed, K. A., Dunbar, C. D., McChesney, J. D., Zaghloul, A. M., and Halim, A. F., 2000.  "Microbial Transformation of Veratrum Alkaloids".  The 41st American Society of Pharmacognosy Annual Meeting, Seattle, Washington
22. El Sayed, K. A., Dunbar, C. D., Hamann, M. T., Mayer, A. M.S., and Pezzuto, J. M., 2000.  "Microbial Transformation of Marine Natural Products".  The 41st American Society of Pharmacognosy Annual Meeting, Seattle, Washington
21. Hashish, N. E., El Sayed, K. A., Hamann, M. T., and Shier, T., 1998.  "Bioactive Marine Secondary Metabolites from The Egyptian Red Sea Coast".  The 39th American Society of Pharmacognosy Annual meeting, Orlanda, Florida
20. Cutler, H. G., Cutler, S. J., Ross, S. A., El Sayed, K. A., Dugan, F. M., Bartlett, M. G., Hill, A. A., Hill, R. A., and Parker, S. R., 1998.  "Koninginin G, A New Metabolite from Trichoderma aureovirid".  The 39th American Society of Pharmacognosy Annual Meeting.  Orlanda, Florida
19. El Sayed, K. A., Dunbar, D. C., and Hamann, M. T., 1998.  "New Manzamines:  Structures, Microbial Bioconversion, Bioactivity and 15N-NMR Studies".  The 39th American Society of Pharmacognosy Annual Meeting, Orlanda, Florida
18. El Sayed, K. A., and Hamann, M. T., 1997.  "Bioactive and Structurally Diverse Secondary Metabolites of Marine Origin."  The National Center for the Development of Natural Products Poster Session
17. El Sayed, K. A, Day, W. B., and Hamann, M. T., 1997.  "Marine Natural Products as Antiinfective Agents."  The 214th American Chemical Society Meeting, Las Vegas, Nevada
16. El Sayed, K. A., and Hamann, M.  T., 1997.  "Microbial Bioconversion Studies of Sarcophine."  The 38th American Society of Pharmacognosy Annual Meeting, Iowa City, Iowa
15. El Sayed, K .A., Dunbar, D.  C., Perry, T. L., Wilkins, S. P., Hamann, M. T., Greenplate, J. T., and Miller-Wideman, M., 1997.  "Marine Natural Products as Prototype Insecticidal Agents".  The 38th American Society of Pharmacognosy Annual Meeting, Iowa City, Iowa
14. Zjawiony, J. K., Hamann, M. T., Slattery, M., Walker, L. A., El Sayed, K. A., and Bartyzel, P., 1996.  "Soft Coral Cembranolides as Prototypes of New Pharmaceutical Agents".  Mississippi-Alabama Sea Grant Consortium Treat, Gulf Shores, Alabama
13. Ross, S. A., El Sayed, K. A., El Sohly, M. A., Hamann, M. T., Abdel-Halim, O. B., Ahmed, A. F., and Ahmed, M. M., 1996.  "Phytochemical Analysis of Geigeria alata and Francoueuria crispa Essential Oils."  The 37th American Society of Pharmacognosy Annual Meeting, Santa Cruz, California
12. El Sayed, K. A., Ross, S. A., El Sohly, M. A., Khalafalla, M. M., Abdel-Halim, O. B., and Ikegamai, F., 1996.  "Effects of Different Levels of Nitrogen and Phosphorus Fertilizers on the Amino Acid, Lipid and Essential Oil composition and Contents of Nigella sativa L. Seeds."  The 37th American Society of Pharmacognosy Annual Meeting, Santa Cruz, California
11. Wilkins, S. P., El Sayed, K. A., Wright, M., Clark, A. M. and Hamann, M. T., 1996.  "Antimycotic Marine Natural Products."  The 37th American Society of Pharmacognosy Annual Meeting, Santa Cruz, California
10. Dunbar, D. C., El Sayed, K. A., Goins, D. K., Janus, S. A., Ager, A. L., and Hamann, M. T., 1996.  "The Antimalarial Activity of Halichondramide, Swinholide A., and other Marine Compounds."  The 37th American Society of Pharmacognosy Annual Meeting, Santa Cruz, California
9. Dunbar, D. C., El Sayed, K. A., Goins, D. K., Janus, S. A., Ager, A. L., and Hamann, M. T., 1996.  "Antimalarial Compounds from Marine Sponges".  23rd MALTO Medicinal Chemistry-Pharmacognosy Meeting at University, Mississipi
8. Hamann, M. T., Wesson, K. J., El Sayed, K. A., and Perry, T. L., 1995.  "Novel Antiinfective and Anticancer Agents from Marin Invertebrates."  Young Investigator Symposium, The 36th American Society of Pharmacognosy Annual Meeting, University, Mississippi
7. El Sayed, K. A., and Hamann, M. T., 1995.  " A New Norcembranoid Dimer from the Red Sea Soft Coral Sinulari gardineri".  The 36th American Society of Pharmacognosy Annual Meeting, University, Mississipp
6. El Sayed, K. A., McChesney, J. D., Halim, A. F., Zaghloul, A. M., and Voehler, M., 1994.  "Tew New Steroidal Alkaloids from Veratrum viride (Ait.) - Liliaceae".  The 3rd International Chemistry & Its Applications Meeting, Mansoura University, Mansoura, Egypt
5. El Sayed, K. A., McChesney, J. D., Halim, A. F., Zaghloul, A. M., and Voehler, M., 1994.  "First Report of Sarcostin Isolation from Cynanchum acutum L. (Asclepiadaceae)."  The 3rd International Chemistry & Its Applications Meeting, Mansoura University, Mansoura, Egypt
4. El Sayed, K. A., Halim, A. F., Zaghloul, A. M., and McChesney, J. D., 1993.  "Veratrum- an Old Hypotensive Revisited."  The 33th American Society of Pharmacognosy Annual Meeting, Williamsburg, Virginia
3. El Sayed, K. A., Halim, A. F., Zaghloul A. M., and McChesney, J. D., 1995.  "Nine New Pregnane Ester Glycosides from Stapelia variegata L.".  The 33th American Society of Pharmacognosy Annual Meeting, Williamsburg, Virginia
2. El Sayed, K. A., Halim, A. F., Zaghloul, A. M., and McChesney, J. D., 1993.  "A Study of Alkaloids in Veratrum viride (Ait.)".  20th MALTO Medicinal Chemistry-Pharmacognosy meeting at Monroe, Louisiana
1. El Sayed, K. A., Halim, A. F., Zaghloul, A. M., and McChesney, J. D., 1992.  "Nine new Pregnane Ester Glycosides from Stapelia variegata L."  19th MALTO Medicinal Chemistry-Pharmacognosy meeting at Little Rock, Arkansas

Patent Inventions:

13. El Sayed KA, Ebrahim H, Mohyledin M, Hailat M. Tobacco cembranoids and metabolites to control angiogenesis-dependent human pathologies. Filed patent#62508605  May 2017
12. El Sayed KA, Siddique AB, Ebrahim H. S(-)-Oleocanthal: Novel isolations, and orally active self-emulsified nano-emulsion for the prevention of breast malignancies recurrence. Provisional patent filed on July 21, 2016. Non-provisional PCT patent filed on July 21, 2017, PCTUS2017/0433208
11. Isothiocycantostilbenes as a novel method and product for treating cancer. Cardelli JA, Gray A, El Sayed KA, Mohyeldin MM. Non-provisional patent submitted on 8/15/2016
10. Semisynthetic olive iridoids based as c-Met/ABL1 inhibitors. El Sayed KA, Mohyeldin MM, Cardelli JA, Dragoi A. Provisional patent submitted on 1/18/2016
9. Eterovic V, and Ferchmin P., El Sayed KA. Tobacco cembranoids as therapeutics for neuronal damage, neurodegenerative diseases and stroke; US9000030B2; US9259400B2; US9259411B2; and  US9278072B2: 2016
8. Neuronal circuit-dependent neuroprotection by interaction between nicotinic receptors.     Ferchmin P., Eterovic VA, Maldonado HM, El Sayed KA. Continuation patent application US9000030B2, issued on 4/7/2015
7. Tocotrienol derivatives and associated methods. Khalid El Sayed, Fathy Behery, Paul Sylvester. U.S. Provisional Application No. 61/566,286. Submitted 12/9/2011, Non-Provisional patent filed on 12/3/2012
6. Tocotrienol esters. Khalid El Sayed, Paul Sylvester. U.S. Provisional Application No. 61/301,665. Submitted 2/5/2010. Non-provisional patent submitted February 1, 2011
5. Latrunculin-based macrolides and their uses. El Sayed KA, Khanfar MA. Patent#: US 20110136880. Submitted 12/8/09
4. Anti-cancer tocotrienol analogues and associated methods. Sylvester PW, El Sayed KA. 2012. US Patent number 8,2687,86
3. Anti-cancer tobacco cembranoids. Khalid El Sayed, Paul Sylvester, Girish Shah. 2012. U.S. Patent Number 7,977,384
2. Anti-cancer phenylmethylene hydantoins. Girish Shah, Khalid EL Sayed. 2011. U.S. Patent Number 8,188,130
1. Hamann, M.T., El Sayed, K.A. 2001. Methods of Treating Drug-Resistant Infections Through Administration of Pharmaceutical Compositions Comprising Manzamine Alkaloids. PCT Int. Appl. WO 2001-2001 US27035 20010829

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