louisiana's college of pharmacy
Curriculum Vitae Scientific Society Offices Publications Lab Teaching Honors/Awards

Publications

Original Peer-Reviewed Research Articles and Reviews
24. Kale, V. M., Mirande, S. R., and Meyer, S. A. (2007)  Comparative cytotoxicity of chloroacetanilide herbicides alachlor, acetochlor and metolachlor in rat and cryopreserved human hepatocytes (submitted).
23. MacMillan, D. K., Hindemith, A. M., Shannon, J. P., Excalon, L. B., Inouye, L. S., and Meyer, S. A. (2007) Distribution of hexahydro-1,3,5-trinitro-1,3,5-triazine degradation products hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (MNX), hexahydro-1,3,5-trinitroso-1,3,5-triazine (TNX) and metabolites in Sprague-Dawley rats. Toxicol. Mechanisms and Methods (in press).
22. Miranda, S. R., and Meyer, S. A. (2007) Cytotoxicity of chloroacetanilide herbicide alachlor in HepG2 cells independent of CYP3A4 and CYP3A7. Food Chem. Toxicol. 45:871-877.
21. Perkins, E., Bao, W., Guan, X., Ang, C. Y., Wolfinger, R. D., Chu, T. M., Gong, P., Meyer, S. A., and Inouye, L. (2006) Comparison of gene expression effects in liver tissue and primary hepatocyte cell cultures after exposure to hexahydro-1,3,5-trinitro-1,3,5-triazine. BMC Bioinformatics 7 (Suppl. 4):S22-28.
20. Meyer, S. A., Marchand, A. J., Hight, J. L., Roberts, G. H., Inouye, L. S., Escalon, L. B. and MacMillan, D. K. (2005) Up-and-down procedure (UDP) determination of acute toxicity of nitroso degradation products of hexahydro-1,3,5-trinitro-1,3,5-triazine. J Appl. Toxicol. 25:427-434.
19. Dalton, S. R., Miller, R. T., and Meyer, S. A. (2003) Hervicide metolachlor induces liver cytochrome P450s 2B1/2 and 3A1/2, but not thyroxine-uridine dinucleotide phosphate glucuronosyltransferase and associated thyroid gland activation. Int. J. Toxicol. 22:387-295.
18. Dalton, S. R., Jirtle, R. L. and Meyer, S. A. (2000) EGF receptors of hepatocytes from rats treated with phenobarbital are sensitized to down-regulatioin by phenobarbital in culture. Toxicol. Appl. Pharmacol. 165:115-126.
17. Wetmore, B. A., Mitchell, A. D., Meyer, S. A., and Genter, M. B. (1999) Evidence for site-specific bioactivatioin of alachlor in the olfactory mucosa of the Long Evans rat. Toxicol. Sci. 49:202-212.
16. Goodell, A. L., Oh, H. S., Meyer, S. A., and Smart, R. C. (1996) Epidermal protein kinase C-B2 is highly sensitive to downregulation and is exclusively expressed in Langerhans cells: Downregulatioin is associated with attenuated contact hypersensitivity. J. Invest. Dermatol. 107:354-359.
15. Meyer, S. A., Kim, T. W., Moser, G. J., Monteiro-Riviere, N. M., and Smart, R. C. (1994) Synergistic interaction between the non-phobol ester-type promoter mirex and 12-O-tetradecanoylphorbol-13-acetate in mouse skin tumor promotion. Carcinogenesis 15:47-52.
14. Meyer, S. A., Moser, G. J., Monteiro-Riviere, N. A., and Smart, R. C. (1993) Minimal role of enhanced cell proliferation in skin tumor promotion by mirex, a new nonphorbol ester-type tumor promoter. Environ. Health Persp. 101 (Suppl 5):265-270.
13. Wasserman, R. H., Chandler, J. S., Meyer, S. A., Smith, C. A., Brindak, M. E., Fullmer, C. S., Penniston, J. T., and Kumar, R. (1992) Intestinal calcium transport and calcium extrusion processes at the basolateral membrane. J. Nutri. 12:662-671.
12. Moser, G. J., Meyer, S. A., and Smart, R. C. (1992) The chlorinated pesticide mirex is a novel non-phorbol ester tumor promoter in mouse skin. Cancer Res. 52:631-636.
11. Jirtle, R. L., Meyer, S. A., and Brockenbrough, J. S. (1991) Liver tumor promoter phenobarbital: A biphasic modulator of hepatocyte proliferation. Prog. Clin. Biol. Res. 369:209-216.
10. Jirtle, R. L. and Meyer, S. A. (1991) Liver tumor promotion: Effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-B1 expression. Digestive Diseases and Sci. 36:659-668.
9. Brockenbrough, J. S., Meyer, S. A., Li, C., and Jirtle, R. L. (1991) A reversible and phorbol ester-specific defect of protein kinase C translocation in hepatocytes isolated from phenobarbital-treated rats. Cancer Res. 51:130-136.
8. Meyer, S. A., Gibbs, T. A., and Jirtle, R. L. (1989) Independent mechanisms for tumor promoters phenobarbital and 12-O-tetradecanoyl-phorbol-13-acetate in reduction of hepatocyte EGF receptors. Cancer Res. 49:5907-5912.
7. Meyer, S. A., Ingraham, C. A., and McCarthy, K. D. (1989) Expression of vimentin by cultured astroglia and oligodendroglia. J. Neurosci. Res. 24:251-259.
6. Meyer, S. A., and Jirtle, R. L. (1989) Phenobarbital decreases EGF receptor expression by cultured hepatocytes independent of protein kinase C. Biochem. Biophys. Res. Commun. 158:652-569.
5. Meyer, S. A., Lin, Z., and Liu, A. Y. C. (1988) Neurite extension and increased expression of RI cAMP-binding protein in ouabain resistant neuroblastoma mutants. J. Neurochem. 51:950-959.
4. Eckl, P. M., Meyer, S. A., Whitcomb, W. R., and Jirtle, R. L. (1988) Phenobarbital reduces EGF receptors and the ability of physiological concentrations of calcium to suppress hepatocyte proliferation. Carcinogenesis 9:479-483.
3. Meyer, S. A., Ewan, R. C., and Beitz, D. B. (1983) Effect of selenium on the subcellular distribution of glutathione peroxidase in rat liver, epididymal fat pad and seminal vesicle. J. Nutr. 113:394-400.
2. Wasserman, R. H., Brinkad, M. E., Meyer, S. A., and Fullmer, C. S. (1982) Evidence for multiple effects of vitamin D3 on calcium absorption: Response of rachitic chicks, with or withouth partial vitamin D3 repletion, to 1,25-dihydroxy-vitamin D3. Proc. Natl. Acad. Sci. USA 79:7939-7943.
1. Meyer, S. A., House, W. A., and Welch, R. M. (1982) Some metabolic interrelations between toxic levels of cadmium and non-toxic levels of selenium fed to rats. J. Nutr. 112:954-961.

Selected Research Abstracts from International and National Meetings

6. Perkins, E. J., Escalon, B. L., Guan, X., and Meyer, S. A. (2007) Genomic analysis of the response and recovery of rat brain from chemically induced seizures. EPA 2007 International Science Forum on Computational Toxicology, May 21-23, 2007, Research Triangle Park, NC.
5. Kale, V. M., Aycock, M. M., Wilbanks, M. S., Perkins, E., Inouye, L. S., and Meyer, S. A. (2007) Hematotoxicity of munititons compound hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and environmental degradation product MNX. The Toxicologist 96 (S-1):35 (Abst. #169)
4. Meyer, S. A. (2006) Persistent anemia associated with hematotoxicity of nitro reduced degradation product MNX of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). 2006 Military Health Research Forum, San Juan, Puerto Rico, May 1-4, 2006.
3. Wetmore, B. A., and Meyer, S. A. (1999) Ethanol inhibits hepatotoxicity of herbicide alachlor. Abstracts of 9th North American ISSX Meeting. October 24-29, 1999. Nashville, TN.
2. Meyer, S. A., and Smart, R. C. (1996) Accelerated malignant conversion of mouse skin tumors co-promoted by mirex and 12-O-tetradecanoyl-phorbol-13-acetate. Proc. Am. Assoc. Cancer Res. 37:157 (Abst. # 1089)
1. Meyer, S. A., and Smart, R. C. (1995) Cell lines from a mouse squamous cell carcinoma with different mutant c-Ha-ras gene dosages characteristic of different stages of carcinogenesis. The Toxicologist 15:55 (Abst. #292)

Book Chapters

6. Wallace, A. D. and Meyer, S. A. Hepatotoxicity. IN:  Molecular and Biochemical Toxicology, 4th Ed. (Hodgson, E. and Smart, R., eds), John Wiley & Sons, New York, (in press)
5. Meyer, S. A.  (2001) Overview of Hepatotoxicity IN: Current Protocols in Toxicology (Maines, M.D., ed), John Wiley & Sons, New York, pp. 14.1.1-14.1.6.
4. Meyer, S. A. (2001) Overview of cellular techniques in toxicology. IN: Introduction to Biochemical Toxicology, 3rd Ed. (Hodgson, E. and Smart, R., eds), John Wiley & Sons, New York, pp. 51-65.
3. Hodgson, E., and Meyer, S. A. (1997) Pesticides IN: Comprehensive Toxicology, Vol. 9, Hepatic and Gastrointestinal Toxicology, Permagon/Elsevier, New York, pp. 369-387
2. Meyer, S. A., Chandler, J. S., and Wasserman, R. H. (1984) Vitamin D and the basolateral calcium pump of chick intestine. IN: Endocrine Control of Bone and  Calcium Metabolism, Vol. 8A (D. V. Cohn, et al., eds) Elsevier, Amsterdam, pp. 253-254.
1. Wasserman, R. H., Shimura, F., Meyer, S. A., and Fullmer, C. S. (1983) Possible roles of vitamin D-induced calcium-binding protein in intestinal calcium transport. IN: Calcium-binding Proteins 1983 (D. deBernard, et at., eds) Elsevier, Amsterdam, pp. 183-188.