| 27. | Berman M, Mattheolabakis G, Suresh M, Amiji M, Reversing epigenetic mechanisms of drug resistance in solid tumors using targeted microRNA delivery, (Expert Opin Drug Deliv. 2016 Apr 29:1-12) |
| 26. | Ryo Hotta, Lily Cheng, Hannah K. Graham, Nandor Nagy, Jaime Belkind-Gerson, George Mattheolabakis, Mansoor M. Amiji, and Allan M. Goldstein, Delivery of enteric neural progenitors with 5-HT4 agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in vivo (Biomaterials, 2016 May; 88:1-11) |
| 25. | Amit Singh, Jing Xu, George Mattheolabakis, and Mansoor Amiji, Redox-Responsive EGFR-Targeted Gelatin Nanoparticles for Combination wt-p53 Plasmid DNA and Gemcitabine Treatment in Pancreatic Cancer Cells, (Nanomedicine. 2015 Dec 3. pii: S1549-9634(15)00217-8. doi: 10.1016/j.nano.2015.11.010) |
| 24. | Lara Milane, Amit Singh, George Mattheolabakis, Megha Suresh, and Mansoor M. Amiji,Exosome Mediated Communication within the tumor microenvironment,J Control Release. 2015 Jul 1. pii: S0168-3659(15)30001-8. doi: 10.1016/j.jconrel.2015.06.029 |
| 23. | George Mattheolabakis, Lara Milane, Amit Singh, Mansoor Amiji, Hyaluronic Acid Targeting of CD44 for Cancer Therapy: From Receptor Biology to Nanomedicine, (Invited review for Special Issue in honor of dr. Langer. J Drug Target, 2015; 23(7–8): 605–618) |
| 22. | Huyen Tran, George Mattheolabakis, Hibah Aldawsari, and Mansoor Amiji. Exosomes as Nanocarriers for Immunotherapy of Cancer and Inflammatory diseases, (Clin Immunol. 2015 Apr 2, pii: S1521-6616(15)00124-2. doi: 10.1016/j.clim.2015.03.021) |
| 21. | George Mattheolabakis, Ioannis Papayannis, Jennifer Yang, Brandon M. Vaeth, Ruixue Wang, Nengtai Ouyang, Basil Rigas and Gerardo G. Mackenzie, Phospho-aspirin (MDC-22) prevents pancreatic carcinogenesis in mice, (Cancer Prev Res(Phila). 2016 Jul; 9(7):624-34) |
| 20. | Lauren E. Bartels, George Mattheolabakis, Joseph F. LaComb, Brandon M Vaeth1, Jizu Zhi, Basil Rigas and Gerardo G. Mackenzie, The novel agent phospho-glycerol-ibuprofen-amide (MDC-330) inhibits glioblastoma growth in mice: An effect mediated by cyclin D1, (Carcinogenesis. 2016 Apr; 37(4):420-9) |
| 19. | Wong, Chi; Cheng, Ka Wing; Papayannis, Ioannis; George Mattheolabakis; Huang, Liqun; Xie, Gang; Ouyang, Nengtai; Rigas, Basil, Phospho-NSAIDs have enhanced efficacy in mice lacking plasma carboxylesterase: Implications for their clinical pharmacology, (Pharm Res. 2014 Nov 13) |
| 18. | George Mattheolabakis, Chi C Wong, Yu Sun, Carol A Amella, Robert Richards, Panayiotis P. Constantinides, Basil Rigas, Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolysable by esterases: A study of phospho-ibuprofen, (Journal of Pharmacology and Experimental Therapeutics, jpet.114.217208; published ahead of print July 21, 2014, doi:10.1124/jpet.114.217208) |
| 17. | Ka Wing Cheng, Ting Nie, Nengtai Ouyanga, Ninche Alston, Chi C. Wong, George Mattheolabakis, Ioannis Papayannis, Liqun Huang, Basil Rigas. A novel ibuprofen derivative with anti-lung cancer properties: Synthesis, formulation, pharmacokinetic and efficacy studies, (International Journal of Pharmaceutics, Oct 2014, doi:10.1016/j.ijpharm.2014.10.019) |
| 16. | Gerardo G. Mackenzie, Liqun Huang, Ninche Alston, Nengtai Ouyang, Kvetoslava Vrankova, George Mattheolabakis, Panayiotis P. Constantinides, Basil Rigas, Targeting Mitochondrial STAT3 with the Novel Phospho-Valproic Acid (MDC-1112) Inhibits Pancreatic Cancer Growth in Mice, (PLOS ONE, May 2013, Volume 8, Issue 5, e61532) |
| 15. | Ka-Wing Cheng , Chi C. Wong , George Mattheolabakis , Gang Xie, Liqun Huang and Basil Rigas, Curcumin enhances the lung cancer chemopreventive efficacy of phospho-sulindac by improving its pharmacokinetics, (Int J Oncol. 2013 Sep;43(3):895-902. doi: 10.3892/ijo.2013.1995. Epub 2013 Jun 27.) |
| 14. | George Mattheolabakis, Gerardo G. Mackenzie, Liqun Huang, Nengtai Ouyang, Ka Wing Cheng, Basil Rigas, Topically applied phospho-sulindac hydrogel is efficacious and safe in the treatment of experimental arthritis in rats, (Pharmaceutical Research, March 2013, DOI 10.1007/s11095-012-0953-8) |
| 13. | George Mattheolabakis, Basil Rigas and Panayiotis P. Constantinides, Nanodelivery Strategies in Cancer Chemotherapy: Biological Rationale and Pharmaceutical Perspectives, (Nanomedicine, 2012 Oct; 7(10):1577-90) |
| 12. | George E. Magoulas, Thomas Garnelis, Constantinos M. Athanassopoulos, Dionissios Papaioannou, George Mattheolabakis, Konstantinos Avgoustakis, Dimitra Hadjipavlou-Litinac, Synthesis and antioxidative/anti-inflammatory activity of novel fullerene–polyamine conjugates, (Tetrahedron, 68, 35, 2 September 2012, 7041–7049) |
| 11. | Ka Wing Cheng, George Mattheolabakis, C. C. Wong, Nengtai Ouyang, Liqun Huang, Panayiotis P. Constantinides and Basil Rigas, Topical phospho-sulindac (OXT-328) is effective in the treatment of non-melanoma skin cancer, (International Journal of Oncology, 2012 Jul 27, DOI: 10.3892/ijo.2012.1577) |
| 10. | Spiridoula Kyriakopoulou, George Mattheolabakis, Sofia Papadimitriou, Evangelos Karavas, Dimitrios Bikiaris and Konstantinos Avgoustakis, PPSu-PEG Copolymers and their Application in the Preparation of Cisplatin-loaded Nanoparticles, (Current nanoscience, 2011, 7, 4, 503-509) |
| 9. | George Mattheolabakis, Ting Nie, Panayiotis P. Constantinides, Basil Rigas, Sterically stabilized liposomes incorporating the novel anticancer agent phospho-ibuprofen (MDC-917): Preparation, characterization and in vitro/in vivo evaluation, (Pharmaceutical Research, 2011, DOI: 10.1007/s11095-011-0619-y) |
| 8. | Zacharoula Iatridi, George Mattheolabakis, Konstantinos Avgoustakis, and Constantinos Tsitsilianisa, Self-assembly and drug delivery studies of pH/thermo-sensitive polyampholytic (A-co-B)-b-C-b-(A-co-B) segmented terpolymers, (Soft matter, 2011, 7, 23, 11160-11168) |
| 7. | Alexandros A. Vassiliou, Sofia A. Papadimitriou, Dimitrios N. Bikiaris, George Mattheolabakis, Konstantinos Avgoustakis, Facile synthesis of polyester-PEG triblock copolymers and preparation of amphiphilic nanoparticles as drug carriers, (Journal of Controlled Release, 148-3, 2010, 388-395) |
| 6. | Bakandritsos A., GeorgeMattheolabakis, Chatzikyriakos G., Szabo T., Tzitzios V., Kouzoudis D., Couris S., Konstantinos Avgoustakis, Doxorubicin Nanocarriers Based on Magnetic Colloids with a Bio-polyelectrolyte Corona and High Non-linear Optical Response: Synthesis, Characterization, and Properties, (Advanced Functional Materials, 2011, 21, 8, 1465-1475) |
| 5. | Blatsios G., Tzimas A., GeorgeMattheolabakis, Panagi Z., Avgoustakis K., Gartaganis S., Development of biodegradable controlled release sclera systems of Triamcinolone acetonide, (Current Eye Research, 2010, 35, 10, 916-924.) |
| 4. | Bakandritsos A., GeorgeMattheolabakis, Zboril R.,Bouropoulos N., Tucek J., Fatouros D., Avgoustakis K., Preparation, stability and cytocompatibility of magnetic/PLA-PEG hybrids, (Nanoscale, 2010, 2, 564–572) |
| 3. | George Mattheolabakis, Lagoumintzis G., Panagi Z.,Papadimitriou E., Partidos C. D., Avgoustakis K., Transcutaneous Delivery of a Nanoencapsulated Antigen: Induction of Immune Responses, (Intern. J. of Pharm. 385, 2010, 187–193) |
| 2. | George Mattheolabakis, Taoufik E., Haralambous S., Roberts M. L., Avgoustakis K., In vivo investigation of tolerance and antitumor activity of cisplatin-loaded PLGA-mPEG nanoparticles, (E. J. Pharm. Biopharm., 2009, 71, 190–195) |
| 1. | Gryparis, E. C., GeorgeMattheolabakis, Bikiaris, D. and Avgoustakis, K. Effect of Conditions of Preparation on the Size and Encapsulation Properties of PLGA-mPEG Nanoparticles of Cisplatin, (Drug Delivery, 2007, 14, 371–380) |
Invited Presentations
Conferences
| 9. | Mattheolabakis G., Papayannis I., Vaeth B.M., Bartels L.E., Ouyang N., Rigas B. and Mackenzie G.G., Phospho-aspirin (MDC-22), a novel aspirin derivative, prevents pancreatic cancer in animal models, AACR Pancreatic Cancer: Innovations in Research and Treatment, 2014 |
| 8. | Mackenzie G.G., Huang L., Alston N., Ouyang N., Vrankova K., Mattheolabakis G., Rigas B., Phopho-valproic acid (MDC-1112): A novel agent against pancreatic cancer, International Journal of Molecular Medicine, 32, S18-S18, 1, Meeting abstract: 156, 2013 |
| 7. | BakandritsosA., MatthaiolabakisG., Avgoustakis K., Winnefeld F., Development of Functional Magnetic, Targeted Carriers for Cationic Drugs, 8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers - Rostock, Germany, 2010 |
| 6. | BakandritsosA., MatthaiolabakisG., Zboril R., Bouropoulos N., Fatouros D., Avgoustakis K., Magnetically Modified Biodegradable Polymeric Nanospheres. 36th CRS Annual Meeting & Exposition, 2009 |
| 5. | Amin F., Mattheolabakis G., Avgoustakis K., Cox P. A., Fatouros D.G., Solubilization of C60 Fullerenes in Amphiphilic Molecules: Formulation Development and Molecular Modeling Studies, 36th CRS Annual Meeting & Exposition, 2009 |
| 4. | Kyriakopoulou S.,Mattheolabakis G.,Papadimitriou S., Karavas E.,Bikiaris D., AvgoustakisK., Synthesis of PPSu-PEG copolymers and their application in the preparation of cisplatin-loaded nanoparticles for tumor targeting, 36th CRS Annual Meeting & Exposition, 2009 |
| 3. | Apostolopoulos N., Mattheolabakis G., Avgoustakis K., Ferderigos N., Leondiadis L., On-resin solid phase peptide synthesis of cell penetrating peptide TAT (47-57) conjugated to PLA-PEG copolymer, 6th Hellenic Forum on Bioactive Peptides 2008 |
| 2. | Mattheolabakis G., Lagoumintzis G.,Panagi Z., Papadimitriou E., Avgoustakis K., Transcutaneous immunization with antigen-loaded PLA nanospheres, 34th CRS Annual Meeting & Exposition, 2007 |
| 1. | Mattheolabakis G., Lagoumintzis G.,Panagi Z., Papadimitriou E., Avgoustakis K., Transcutaneous immunization with antigen-loaded PLA nanospheres, 5th Hellenic Forum on Bioactive Peptides 2007 |